2. Academic Validation
  3. Justicisaponin-I, a new triterpenoid saponin from Justicia simplex

Justicisaponin-I, a new triterpenoid saponin from Justicia simplex

  • Planta Med. 1981 Jul;42(7):279-83. doi: 10.1055/s-2007-971641.
S Ghosal 1,  A K Srivastava,  R S Srivastava,  S Chattopadhyay,  M Maitra
Affiliations

Affiliation

  • 1 Department of Pharmaceutics, Banaras Hindu University, Varanasi-5.
PMID: 17401975 DOI: 10.1055/s-2007-971641
Abstract

A new triterpenoid saponin, named justicisaponin-I, has been isolated from Justicia simplex D. Don. (Acanthaceae). It has been assigned oleanolic acid-3-O-beta-D-glucopyranosyl-4'-O-ferulate structure (1) on the basis of chemical transformation and comprehensive spectral evidence. Justicisaponin-I has produced significant sperm acrosomal membrane stabilizing action and may prove to be a potent antifertility agent.

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