2. Academic Validation
  3. Novoamauromine and ent-Cycloechinulin: two new diketopiperazine derivatives from Aspergillus novofumigatus

Novoamauromine and ent-Cycloechinulin: two new diketopiperazine derivatives from Aspergillus novofumigatus

  • Chem Pharm Bull (Tokyo). 2010 May;58(5):717-9. doi: 10.1248/cpb.58.717.
Kazuki Ishikawa 1,  Tomoo Hosoe,  Takeshi Itabashi,  Daigo Wakana,  Kayoko Takizawa,  Takashi Yaguchi,  Ken-ichi Kawai
Affiliations

Affiliation

  • 1 Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142-8501, Japan.
PMID: 20460802 DOI: 10.1248/cpb.58.717
Abstract

Two new diketopiperazine metabolites, novoamauromine (1) and ent-cycloechinulin (2) have been isolated from Aspergillus novofumigatus CBS117520. The structures of 1 and 2 were established on the basis of spectroscopic and chemical investigation, including a detailed comparison of the spectroscopic and physico-chemical data of amauromine (3) and cycloechinulin (4).

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