RNA nanotherapeutics with fibrosis overexpression and retention for MASH treatment

Affiliations

• 1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
• 2 Beijing Key Laboratory of Molecular Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China.
• 3 Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, China.
• 4 Institute of Cardiovascular Sciences and State Key Laboratory of Vascular Homeostasis and Remodeling, School of Basic Medical Sciences, Peking University, Beijing, China.
• 5 Chinese Institute for Brain Research, Beijing, China.
• 6 China Spallation Neutron Source, Institute of High Energy Physics, Chinese Academy of Science, Dongguan, China.
• 7 Department of Surgery, Nantong Tumor Hospital, Tumor Hospital Affiliated to Nantong University, Nantong, China.
• 8 Keymed Biosciences (Chengdu) Limited, Chengdu, Sichuan, China.
• 9 Key Laboratory of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
• 10 MOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, China.
• 11 Interdisplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
• 12 Department of Bioengineering, UC Berkeley, Berkeley, CA, USA.
• 13 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China. lmiao_pharm@bjmu.edu.cn.
• 14 Beijing Key Laboratory of Molecular Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China. lmiao_pharm@bjmu.edu.cn.
• 15 Peking University-Yunnan Baiyao International Medical Research Center, Beijing, China. lmiao_pharm@bjmu.edu.cn.
• # Contributed equally.