2. Academic Validation
  3. Myxothiazol, a new antibiotic interfering with respiration

Myxothiazol, a new antibiotic interfering with respiration

  • Antimicrob Agents Chemother. 1981 Apr;19(4):504-7. doi: 10.1128/AAC.19.4.504.
G Thierbach,  H Reichenbach
PMID: 7247372 DOI: 10.1128/AAC.19.4.504
Abstract

Myxothiazol, a new Antibiotic from the myxobacterium Myxococcus fulvus, inhibited the growth of many yeasts and fungi at concentrations between 0.01 and 3 micrograms/ml. It was generally inactive against bacteria. The inhibitory effect was cytostatic. With Candida albicans, Saccharomyces cerevisiae, and Mucor hiemalis, the growth inhibition was neutralized by glucose. Soon after being added to a cell suspension, the compound almost completely blocked oxygen consumption.

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