1. Metabolic Enzyme/Protease Apoptosis Anti-infection
  2. Ser/Thr Protease Apoptosis SARS-CoV
  3. Nafamostat formate salt-13C6

Nafamostat formate salt-13C6  (Synonyms: 萘莫司他-13C6)

目录号: HY-B0190S1 纯度: 95.90%
COA 产品使用指南 技术支持

Nafamostat formate salt-13C613C 标记的 Nafamostat。 Nafamostat 是广谱的丝氨酸蛋白酶抑制剂,血管舒缓素抑制剂,能抑制血液凝固,还是潜在的补体抑制剂。Nafamostat 通过降低颗粒酶活性和 CTL 细胞溶解抑制T细胞自身反应活性。Nafamostat 可抑制SARS-CoV-2 的激活。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Nafamostat formate salt-<sup>13</sup>C<sub>6</sub> Chemical Structure

Nafamostat formate salt-13C6 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货
500 μg ¥12000
询问价格 & 货期

* Please select Quantity before adding items.

Other Forms of Nafamostat formate salt-13C6:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nafamostat formate salt-13C6 is the 13C labeled Nafamostat. Nafamostat, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis. Nafamostat blocks activation of SARS-CoV-2[1][2][3][4][5].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

445.38

Formula

C1513C6H21N5O6

非标记 CAS
性状

固体

颜色

White to off-white

中文名称

萘莫司他-13C6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 35 mg/mL (78.58 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.2453 mL 11.2264 mL 22.4527 mL
5 mM 0.4491 mL 2.2453 mL 4.4905 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2453 mL 11.2264 mL 22.4527 mL 56.1318 mL
5 mM 0.4491 mL 2.2453 mL 4.4905 mL 11.2264 mL
10 mM 0.2245 mL 1.1226 mL 2.2453 mL 5.6132 mL
15 mM 0.1497 mL 0.7484 mL 1.4968 mL 3.7421 mL
20 mM 0.1123 mL 0.5613 mL 1.1226 mL 2.8066 mL
25 mM 0.0898 mL 0.4491 mL 0.8981 mL 2.2453 mL
30 mM 0.0748 mL 0.3742 mL 0.7484 mL 1.8711 mL
40 mM 0.0561 mL 0.2807 mL 0.5613 mL 1.4033 mL
50 mM 0.0449 mL 0.2245 mL 0.4491 mL 1.1226 mL
60 mM 0.0374 mL 0.1871 mL 0.3742 mL 0.9355 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nafamostat formate salt-13C6
目录号:
HY-B0190S1
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