2. Anti-infection Apoptosis JAK/STAT Signaling Stem Cell/Wnt Cell Cycle/DNA Damage MAPK/ERK Pathway Protein Tyrosine Kinase/RTK NF-κB
  3. Parasite Apoptosis STAT Topoisomerase ERK FAK p38 MAPK NF-κB
  4. Nitidine chloride (Standard)

Nitidine chloride (Standard)  (Synonyms: 氯化两面针碱 (Standard))

目录号: HY-N0498R 纯度: ≥98%
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摩尔计算器

Nitidine (chloride) (Standard) 是 Nitidine (chloride) 的分析标准品。本产品用于研究及分析应用。Nitidine chloride 是可从Zanthoxylum nitidum (Roxb) DC 中分离得到一种具有抗疟疾活性的化合物。Nitidine chloride 通过多个靶点通路，发挥抗癌活性，如诱导凋亡，抑制STAT3、DNA拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。Nitidine chloride通过MAPK和NF-kB途径抑制Lps诱导的炎性细胞因子的产生。

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Nitidine chloride (Standard) Chemical Structure

Nitidine chloride (Standard) Chemical Structure

CAS No. : 13063-04-2

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生物活性

Nitidine (chloride) (Standard) is the analytical standard of Nitidine (chloride). This product is intended for research and analytical applications. Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway.

分子量

383.82

Formula

C21H18ClNO4
CAS 号
中文名称

氯化两面针碱 (Standard)
结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Nitidine chloride (Standard) 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nitidine chloride (Standard)13063-04-2氯化两面针碱 (Standard)ParasiteApoptosisSTATTopoisomeraseERKFAKp38 MAPKNF-κBExtracellular signal regulated kinasesPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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