2. 天然产物
  3. 植物 生物碱
  4. 三白草科 哌啶类生物碱
  5. 鱼腥草
  6. Norcepharadione B

Norcepharadione B 是从 Houttuynia cordata 中分离得到的生物碱。Norcepharadione B 对 A-549、SK-OV-3、SK-MEL-2、XF-498 和 HCT-15 细胞具有中等的细胞毒性，其ED50 分别为 40、26.4、40、14.2 和 38.2 μg/mL。

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Norcepharadione B Chemical Structure

Norcepharadione B Chemical Structure

CAS No. : 57576-41-7

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Norcepharadione B 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Norcepharadione B is an alkaloid that can be isolated from Houttuynia cordata. Norcepharadione B exhibits moderate cytotoxicity against A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cell line with ED50s of 40, 26.4, 40, 14.2 and 38.2 μg/mL, respectively[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BV-2 IC50
37 μM
Compound: 14
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay
[PMID: 33822610]
分子量

307.30

Formula

C18H13NO4
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Norcepharadione B 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Norcepharadione B57576-41-7OthersHouttuynia cordataCytotoxicityAlkaloidA-549SK-OV-3SK-MEL-2XF-498HCT-15Inhibitorinhibitorinhibit

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