2. Immunology/Inflammation TGF-beta/Smad Stem Cell/Wnt GPCR/G Protein
  3. Transmembrane Glycoprotein Prostaglandin Receptor PKA COX
  4. Prostaglandin E3

Prostaglandin E3 是一种源自二十碳五烯酸的类二十烷酸。Prostaglandin E3 抑制向 M1 巨噬细胞的极化，但促进 M2a 巨噬细胞的极化。Prostaglandin E3 具有抗炎和抗肿瘤活性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Prostaglandin E3 Chemical Structure

Prostaglandin E3 Chemical Structure

CAS No. : 802-31-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货
50 μg (1.43 mM * 100 μL in Methyl acetate) ￥3700
询问价格 & 货期
100 μg (1.43 mM * 200 μL in Methyl acetate) 现货 询问价格 & 货期

* Please select Quantity before adding items.

Customer Review

Other Forms of Prostaglandin E3:

Prostaglandin E3 相关抗体

Top Publications Citing Use of Products

查看 Prostaglandin Receptor 亚型特异性产品:

查看所有亚型
DP EP FP IP TXA2/TP TXB2

查看 PKA 亚型特异性产品:

查看所有亚型
PKA PKAR

查看 COX 亚型特异性产品:

查看所有亚型
COX COX-1 COX-2 COX-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Prostaglandin E3 is an eicosanoid derived from eicosapentaenoic acid. Prostaglandin E3 inhibits polarization towards M1 but promotes polarization of M2a macrophages. Prostaglandin E3 shows anti-inflammatory and anti-tumor activity[1].

体外研究
(In Vitro)

Prostaglandin E3 (1-10000 nM) 在极化巨噬细胞中抑制 M1 并诱导 M2a 标记物表达[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Prostaglandin E3 相关抗体:
体内研究
(In Vivo)

Prostaglandin E3 (1 µmol/L; i.p.) 在 LPS (HY-D1056) (5 mg/kg) 诱导急性炎症模型中调节巨噬细胞极化以发挥抗炎功能[1]。
Prostaglandin E3 (1 µmol/L; every 3 days for 4 weeks) 通过调节巨噬细胞极化表现出抗肿瘤活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 5 weeks, Nude mice (BABL/c) (PC3 xenograft model)[1]
Dosage: 1 µmol/L for 50 µL
Administration: Injected next to the tumour, every 3 days for 4 weeks
Result: Decreased the weights of transplanted tumours, inhibits the expression of CD68 and CD206.
Animal Model: 6-8-week-old C57BL6/J mice[1]
Dosage: LPS+ PGE3 (5 mg/kg + 1 µmol/L)
Administration: I.p.; once
Result: Significantly reduced MPMs with an M1-like phenotype and increased M2-like MPMs, inhibited inflammatory cytokine secretion in both the serum and MPM cell lysates.
分子量

350.45

Formula

C20H30O5
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
纯度 & 产品资料

纯度: ≥99.0%

COA (293 KB)

产品使用指南 (1538 KB)
参考文献

Prostaglandin E3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prostaglandin E3802-31-3Prostaglandin E 3Prostaglandin E-3Transmembrane GlycoproteinProstaglandin ReceptorPKACOXProtein kinase ACyclooxygenasemacrophageanti-inflammatoryanti-tumorM2aInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Prostaglandin E3
目录号：
HY-113481
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z