2. Apoptosis
  3. Ferroptosis
  4. (R)-HTS-3

(R)-HTS-3 是溶血磷脂酰胆碱酰基转移酶 (LPCAT3) 的抑制剂，其 IC50 只为 0.09 μM。(R)-HTS-3 抑制 PE, PC 和 PS 的 c20:4 含量，同时促进 C22:4 磷脂的相应升高和 20:4 磷脂酰肌醇 (PI) 脂的增加。

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(R)-HTS-3 Chemical Structure

(R)-HTS-3 Chemical Structure

CAS No. : 2771208-83-2

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(R)-HTS-3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R)-HTS-3 is an lysophosphatidylcholine acyltransferase 3 (LPCAT3) inhibitor, with an IC50 of 0.09 μM. (R)-HTS-3 suppresses the C20:4 content of PE, PC, and PS, while promoting a correspondingelevation in C22:4 phospholipids and a paradoxical increase in C20:4 phosphatidylinositol (PI) lipids[1].

体外研究
(In Vitro)

(R)-HTS-3 (10 µM) 可缓解 RSL3 诱导的 HT-1080 和 786-O 癌细胞铁死亡。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(R)-HTS-3 相关抗体:
分子量

304.33

Formula

C17H18F2N2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(R)-HTS-3 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

(R)-HTS-32771208-83-2FerroptosisInhibitorinhibitorinhibit

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