2. Immunology/Inflammation
  3. NO Synthase COX Interleukin Related
  4. (rac)-Poriol

(rac)-Poriol  (Synonyms: 5,7,4'-Trihydroxy-6-methylflavanone)

目录号: HY-N9086A
产品使用指南 技术支持

(rac)-Poriol (5,7,4'-Trihydroxy-6-methylflavanone) 具有抗氧化活性，可清除自由基 DPPH，IC50 为 0.18 µg/mL。 (rac)-Poriol 可在 RAW264.7 中抑制 LPS (HY-D1056) 诱导的 NO 生成（10 μM 时抑制率为 98.35%），并具有抗炎活性。 (rac)-Poriol 与 iNOS、COX-1、COX-2、TNF-α 和 IL-1β 具有良好的结合亲和力。

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(rac)-Poriol Chemical Structure

(rac)-Poriol Chemical Structure

CAS No. : 70460-58-1

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Other Forms of (rac)-Poriol:

(rac)-Poriol 相关抗体

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nNOS iNOS eNOS

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(rac)-Poriol (5,7,4'-Trihydroxy-6-methylflavanone) exhibits antioxidant activity, and scavenges free radical DPPH with an IC50 of 0.18 µg/mL. (rac)-Poriol inhibits the LPS (HY-D1056)-induced NO generation in RAW264.7 (98.35% inhibition rate at 10 μM), and exhibits anti-inflammatory activity. (rac)-Poriol exhibits good binding affinity with iNOS, COX-1, COX-2, TNF-α, and IL-1β[1].

分子量

286.28

Formula

C16H14O5
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(rac)-Poriol 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(rac)-Poriol70460-58-15,7,4'-Trihydroxy-6-methylflavanoneNO SynthaseCOXInterleukin RelatedNitric oxide synthasesNOSCyclooxygenaseILRAW264.7antioxidantInhibitorinhibitorinhibit

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