2. 重组蛋白
  3. Receptor Proteins
  4. ADCYAP1R1 蛋白, Human (HEK293, Fc)

ADCYAP1R1 蛋白, Human (HEK293, Fc)

目录号: HY-P77120
COA 产品使用指南

ADCYAP1R1 蛋白是垂体腺苷酸环化酶激活多肽 (PACAP) 的受体，可识别 PACAP-27 和 PACAP-38。通过 G 蛋白，该受体激活腺苷酸环化酶，启动多个下游信号通路。ADCYAP1R1 蛋白, Human (HEK293, Fc) 是重组的 ADCYAP1R1 蛋白，由 HEK293 表达，带有 C-hFc 标签。ADCYAP1R1 蛋白, Human (HEK293, Fc) 全长 155 个氨基酸，分子量约为 ~65 kDa。

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规格 价格 是否有货 数量
5 μg ￥800 In-stock
10 μg ￥1360 In-stock
50 μg ￥3800 In-stock
100 μg   询价  

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描述

The ADCYAP1R1 protein is a receptor for pituitary adenylate cyclase-activating polypeptide (PACAP) and recognizes PACAP-27 and PACAP-38. Through the G protein, this receptor activates adenylyl cyclase, initiating multiple downstream signaling pathways. ADCYAP1R1 Protein, Human (HEK293, Fc) is the recombinant human-derived ADCYAP1R1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ADCYAP1R1 Protein, Human (HEK293, Fc) is 155 a.a., with molecular weight of ~65 kDa.
研究背景

ADCYAP1R1 蛋白充当垂体腺苷酸环化酶激活多肽 (PACAP) 的受体，特异性识别 PACAP-27 和 PACAP-38。该受体通过 G 蛋白运作，激活腺苷酸环化酶，启动下游信号通路。它参与多种激素释放的调节，包括促肾上腺皮质激素、黄体生成素、生长激素、催乳素、肾上腺素和儿茶酚胺。此外，ADCYAP1R1 可能在精子发生和精子活力中发挥作用，有助于平滑肌松弛和胃肠道分泌。它与 PACAP 的相互作用是通过 N 端细胞外结构域促进的，突出了它在多种生理过程中的重要参与。
种属

Human
表达系统

HEK293
标签

C-hFc
蛋白编号

P41586 (M1-A155)
基因 ID

117  [NCBI]
蛋白结构
N-term
ADCYAP1R1 (M1-A155)
Accession # P41586
hFc
C-term
同用名
Pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; ADCYAP1R1
分子量

Approximately 65 kDa
纯度

Greater than 88% as determined by reducing SDS-PAGE
性状

溶液
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (209 KB)

产品使用指南 (1213 KB)

ADCYAP1R1 Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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