1. 重组蛋白
  2. CD Antigens
  3. CD1D 蛋白, Human (His-SUMO)

CD1D 蛋白, Human (His-SUMO)

目录号: HY-P74327A
产品使用指南

CD1D 蛋白是一种关键的抗原呈递分子,可结合自身和非自身糖脂,将它们呈递给自然杀伤 T 细胞上的 T 细胞受体。它与 B2M 合作,集中协调免疫反应,并且它与 MHC II 的相互作用强调了它在复杂的免疫系统调节网络中的重要性。CD1D 蛋白, Human (His-SUMO) 是重组的 CD1D 蛋白,由 E. coli 表达,带有 N-6*His, N-SUMO 标签。CD1D 蛋白, Human (His-SUMO) 全长 282 个氨基酸

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描述

The CD1D protein, a key antigen-presenting molecule, binds self and non-self glycolipids, presenting them to T-cell receptors on natural killer T-cells. Partnering with B2M, it centrally orchestrates immune responses, and its interactions with MHC II emphasize its significance in the intricate network of immune system regulation. CD1D Protein, Human (His-SUMO) is the recombinant human-derived CD1D, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of CD1D Protein, Human (His-SUMO) is 282 a.a.,

研究背景

CD1D-B2M 异二聚体蛋白是一种重要的抗原呈递分子,具有结合自身和非自身糖脂的独特能力,促进其呈递给自然杀伤 T 细胞上的 T 细胞受体。该蛋白质与 B2M(β-2-微球蛋白)形成异二聚体复合物,在协调免疫反应中发挥着核心作用。它与 MHC II 的相互作用进一步增强了它在复杂的免疫系统调节网络中的重要性。

种属

Human

表达系统

E. coli

标签

N-6*His;N-SUMO

蛋白编号

P15813(E20-S301)

基因 ID

912

同用名
Antigen-presenting glycoprotein CD1d; CD1.1; CD1A; CD1d; CD1D antigen; CD1D antigen d polypeptide; CD1d molecule; CD1D_HUMAN; Cd1d1 ; differentiation antigen CD1 alpha 3 ; HMC class I antigen like glycoprotein CD1D ; Ly 38; MGC34622; R3; R3G1; T cell surface glycoprotein CD1d ; Thymocyte antigen CD1D
氨基酸序列

EVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTS

分子量

Approximately 47.9 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CD1D Protein, Human (His-SUMO) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD1D Protein, Human (His-SUMO)
目录号:
HY-P74327A
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