LILRA1/LIR-6/CD85i 蛋白, Human (HEK293, His)

LILRA1/LIR-6/CD85i protein serves as a receptor for class I MHC antigens and plays a crucial role in immune recognition and response. Its interaction with class I MHC molecules suggests involvement in monitoring and possibly influencing immune activity. LILRA1/LIR-6/CD85i Protein, Human (HEK293, His) is the recombinant human-derived LILRA1/LIR-6/CD85i protein, expressed by HEK293 , with C-His labeled tag. The total length of LILRA1/LIR-6/CD85i Protein, Human (HEK293, His) is 445 a.a., with molecular weight of ~50 KDa.

LILRA1/LIR-6/CD85i 蛋白似乎是 I 类 MHC 抗原的受体，表明在免疫识别和反应中发挥着至关重要的作用。它与 I 类 MHC 分子的相互作用表明参与监测并可能影响免疫活动。作为受体，LILRA1 可能有助于对呈递 I 类 MHC 抗原的细胞进行微调识别，从而在免疫监视中发挥关键作用。进一步研究 LILRA1 的相互作用及其对免疫信号的影响可以加深我们对其作为受体的功能及其在免疫监视和调节过程中的潜在影响的理解。

Measured by its binding ability in a functional ELISA. Immobilized Human LILRA1 at 2 μg/mL (100 μL/well) can bind Human ANGPTL7, The ED₅₀ for this effect is 1.143 μg/mL.

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  Measured by its binding ability in a functional ELISA. Immobilized Human LILRA1 at 2 μg/mL (100 μL/well) can bind Human ANGPTL7, The ED₅₀ for this effect is 1.143 μg/mL.

Human

HEK293

C-His

O75019-1 (P17-N461)

11024  [NCBI]

PRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSGAAETLSPPQNKSDSKAGAANTLSPSQNKTASHPQDYTVEN

Approximately 70-75 kDa due to the glycosylation

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.