PIG3 蛋白, Human (His)

PIG3 is a key player in cellular processes, functioning as an enzyme that catalyzes NADPH-dependent quinone reduction. It exhibits moderate enzymatic activity towards β-naphthoquinone, with the para -quinone isomer (1,2-β-naphthoquinone) compared to the para -isomer (1,4-β-naphthoquinone). Obvious preference. PIG3 Protein, Human (His) is the recombinant human-derived PIG3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PIG3 Protein, Human (His) is 332 a.a., with molecular weight of ~37.5 kDa.

PIG3（或 p53 诱导基因 3）是一种催化 NADPH 依赖性醌还原的蛋白质，显示出对邻醌异构体（1,2-β-萘醌）的偏好超过对位异构体（1,4-β） -萘醌）。此外，PIG3 对 β-萘醌表现出较低的酶活性，并且在体外对非醌化合物（例如二胺和 2,6-二氯靛酚）表现出还原酶活性。除了其酶促功能外，PIG3 还参与活性氧 (ROS) 的生成。这种多方面的作用表明，PIG3 可能通过参与醌还原和其他还原酶活性来促进氧化还原稳态，同时还参与 ROS 的产生，突出了其对细胞氧化应激反应的潜在影响。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-6*His

Q53FA7 (M1-Q332)

9540  [NCBI]

MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ

Approximately 37.5 kDa

• 
  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of sterile 50mM Tris-HCL, 300mM NaCl, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween 80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.