PSMA 蛋白, Mouse (Biotinylated, HEK293, His)

The PSMA protein is a multifunctional enzyme with folate hydrolase and NAALADase activities and a preference for tri-alpha-glutamic acid peptides. It absorbs folate in the intestines, aids in important metabolic processes, and modulates excitatory neurotransmission in the brain by hydrolyzing NAAG to release glutamate. PSMA Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived PSMA protein, expressed by HEK293 , with N-His labeled tag. The total length of PSMA Protein, Mouse (Biotinylated, HEK293, His) is 708 a.a., with molecular weight of 90-110 kDa.

PSMA 是一种多功能酶，具有叶酸水解酶和 N-乙酰化-α-连接酸性二肽酶 (NAALADase) 活性，尤其偏爱三-α-谷氨酸肽。它在肠道吸收叶酸方面发挥着至关重要的作用，有助于重要的代谢过程。在大脑内，PSMA 通过水解神经肽 N-乙酰天冬氨酰谷氨酸 (NAAG) 从而释放谷氨酸，从而充当兴奋性神经传递的调节剂。此外，它还表现出二肽基肽酶 IV 型活性，并在体外有效裂解 Gly-Pro-AMC，展示了其多功能的酶功能。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Mouse

HEK293

N-His

O35409 (K45-A752)

53320  [NCBI]

KPSNEATGNVSHSGMKKEFLHELKAENIKKFLYNFTRTPHLAGTQNNFELAKQIHDQWKEFGLDLVELSHYDVLLSYPNKTHPNYISIINEDGNEIFKTSLSEQPPPGYENISDVVPPYSAFSPQGTPEGDLVYVNYARTEDFFKLEREMKISCSGKIVIARYGKVFRGNMVKNAQLAGAKGMILYSDPADYFVPAVKSYPDGWNLPGGGVQRGNVLNLNGAGDPLTPGYPANEHAYRHELTNAVGLPSIPVHPIGYDDAQKLLEHMGGPAPPDSSWKGGLKVPYNVGPGFAGNFSTQKVKMHIHSYTKVTRIYNVIGTLKGALEPDRYVILGGHRDAWVFGGIDPQSGAAVVHEIVRSFGTLKKKGRRPRRTILFASWDAEEFGLLGSTEWAEEHSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELQSPDEGFEGKSLYDSWKEKSPSPEFIGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWKTNKVSSYPLYHSVYETYELVVKFYDPTFKYHLTVAQVRGAMVFELANSIVLPFDCQSYAVALKKYADTIYNISMKHPQEMKAYMISFDSLFSAVNNFTDVASKFNQRLQELDKSNPILLRIMNDQLMYLERAFIDPLGLPGRPFYRHIIYAPSSHNKYAGESFPGIYDALFDISSKVNASKAWNEVKRQISIATFTVQAAAETLREVA

90-110 kDa

Greater than 95% as determined by Tris-Bis PAGE

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.