ST6GAL1 蛋白, Rat (HEK293, His)

The ST6GAL1 protein is responsible for facilitating the transfer of sialic acid from CMP-sialic acid to galactose-containing receptor substrates. Sialic acid is an important component of a variety of glycoproteins and glycolipids, and ST6GAL1 protein-mediated sialic acid transfer plays a crucial role in regulating the structure and function of these molecules. ST6GAL1 Protein, Rat (HEK293, His) is the recombinant rat-derived ST6GAL1 protein, expressed by HEK293 , with N-His labeled tag. The total length of ST6GAL1 Protein, Rat (HEK293, His) is 377 a.a., with molecular weight of 47-57 kDa.

ST6GAL1 蛋白负责促进唾液酸从 CMP-唾液酸转移到含有半乳糖的受体底物。唾液酸是多种糖蛋白和糖脂的重要组成部分，ST6GAL1蛋白介导的唾液酸转移在调节这些分子的结构和功能中发挥着至关重要的作用。通过将唾液酸附着到受体底物上的半乳糖残基上，ST6GAL1 蛋白影响细胞过程，例如细胞粘附、信号传导和免疫反应。这种酶活性对于许多生物系统的正常运作至关重要，了解 ST6GAL1 蛋白的作用可能会对免疫学、癌症研究和糖工程等各个领域产生影响。

Measured by its ability to transfer Neu5Ac from CMP-Neu5Ac to N-Acetyllactosamine that incubate at 37°C for 20min. The specific activity is 288.256 pmol/min/μg.

Rat

HEK293

N-6*His

P13721-1/NP_001106815.1 (K27-C403)

25197  [NCBI]

KKGSDYEALTLQAKEFQMPKSQEKVAMGSASQVVFSNSKQDPKEDIPILSYHRVTAKVKPQPSFQVWDKDSTYSKLNPRLLKIWRNYLNMNKYKVSYKGPGPGVKFSVEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKVGPWQRCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGSKTTIRLMNSQLVTTEKRFLKDSLYTEGILIVWDPSVYHADIPKWYQKPDYNFFETYKSYRRLNPSQPFYILKPQMPWELWDIIQEISADLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYHPLLFEKNMVKHLNEGTDEDIYLFGKATLSGFRNIRC

Approximately 47-57 kDa due to the glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.