THSD7A 蛋白, Human (HEK293, His)

THSD7A Protein orchestrates actin cytoskeleton rearrangement, actively influencing cellular dynamics. Its soluble form facilitates endothelial cell migration and filopodia formation in sprouting angiogenesis, relying on Focal Adhesion Kinase (FAK) activation. This emphasizes THSD7A's role in modulating key cellular processes associated with angiogenesis, highlighting its potential as a regulator of vascular development. THSD7A Protein, Human (HEK293, His) is the recombinant human-derived THSD7A protein, expressed by HEK293 , with C-His labeled tag. The total length of THSD7A Protein, Human (HEK293, His) is 1560 a.a., with molecular weight of 180-240 kDa.

THSD7A 协调肌动蛋白细胞骨架重排，对细胞动力学产生影响。值得注意的是，其可溶形式在血管生成的背景下作为内皮细胞迁移和丝状伪足形成的促进剂，通过依赖于 FAK（粘着斑激酶）激活的机制发挥作用。这强调了它积极参与调节与血管生成相关的关键细胞过程，并强调了它作为血管发育调节剂的潜力。

Human

HEK293

C-His

Q9UPZ6 (A48-W1607)

221981  [NCBI]

180-240 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4)

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.