TSC22/TSC22D1 蛋白, Mouse (His)

TSC22D1 protein, possessing RNA polymerase II binding activity, regulates apoptotic and cell proliferation processes. It is found in the cytoplasm and nucleus and expressed in multiple structures like the alimentary system and central nervous system. With ubiquitous expression observed, TSC22D1 likely regulates diverse cellular processes across tissues. TSC22/TSC22D1 Protein, Mouse (His) is the recombinant mouse-derived TSC22/TSC22D1 protein, expressed by E. coli , with N-His labeled tag.

TSC22D1 蛋白预计具有 DNA 结合转录激活剂活性，特别是 RNA 聚合酶 II 和 RNA 聚合酶 II 顺式调控区序列特异性 DNA 结合活性。它在细胞凋亡过程的负调控、凋亡过程的正调控和细胞群增殖的正调控等过程的上游发挥作用，存在于细胞质和细胞核中。TSC22D1 的表达跨越多种结构，包括消化系统、中枢神经系统、早期受孕、泌尿生殖系统和感觉器官。在胚胎第 14 天时，在肾上腺和中枢神经系统等组织中观察到 TSC22D1 普遍表达，TSC22D1 可能在不同组织的多种细胞过程中发挥调节作用。

Mouse

E. coli

N-His

NP_033392 (M1-A143)

21807  [NCBI]

Approximately 17.8 kDa.

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.