1. Neuronal Signaling
  2. Imidazoline Receptor
  3. RS 45041-190 hydrochloride

RS 45041-190 hydrochloride 是一种对 I2 咪唑啉受体 (I2 imidazoline receptors) 具有高亲和力的配体,在大鼠、兔、狗和狒狒肾脏中的 pKi 分别为 8.66、9.37、9.32 和 8.85。RS 45041-190 hydrochloride 在体外对单胺氧化酶 A (monoamine oxidase A) 具有中等抑制效力(pIC50= 6.12),但对单胺氧化酶 B (monoamine oxidase B) 的抑制效力要低得多(pIC50 = 4.47)。

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RS 45041-190 hydrochloride Chemical Structure

RS 45041-190 hydrochloride Chemical Structure

CAS No. : 204274-74-8

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  • 生物活性

  • 纯度 & 产品资料

生物活性

RS 45041-190 hydrochloride is a high-affinity ligand for I2 imidazoline receptors, with the pKis of 8.66, 9.37, 9.32, and 8.85 in rat, rabbit, dog and baboon kidney, respectively. RS 45041-190 hydrochloride shows moderate potency for the inhibition of monoamine oxidase A in vitro (pIC50= 6.12), but had much lower potency for monoamine oxidase B (pIC50 = 4.47)[1].

分子量

258.15

Formula

C11H13Cl2N3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

RS 45041-190 hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RS 45041-190 hydrochloride
目录号:
HY-101301A
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