1. Immunology/Inflammation Apoptosis NF-κB
  2. NO Synthase TNF Receptor NF-κB COX Interleukin Related
  3. Sabialimon P

Sabialimon P (compound 16) 是一种 NO 释放抑制剂 (IC50=18.12 μM),具有抗炎活性。Sabialimon P 显著降低 LPS (HY-D1056) 诱导的 RAW264.7 细胞中 TNF-αiNOSIL-6NF-κB 的分泌,抑制 COX-2NF-κB/p65 的表达。

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Sabialimon P Chemical Structure

Sabialimon P Chemical Structure

CAS No. : 2267333-96-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sabialimon P (compound 16) is a NO release inhibitor (IC50=18.12 μM) with anti-inflammatory activity. Sabialimon P significantly reduces the secretion of TNF-α, iNOS, IL-6 and NF-κB and inhibits the expression of COX-2 and NF-κB/p65 in RAW264.7 cells induced by LPS (HY-D1056)[1].

分子量

486.73

Formula

C31H50O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Sabialimon P
目录号:
HY-159516
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