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  6. Scillascillin

Scillascillin (compound 10) 是一种高异黄烷酮。Scillascillin 可以从 S. scilloides 中分离出来。Scillascillin 对 MCF-7 (乳腺癌) 和 DU-145 (前列腺癌) 细胞具有抗癌活性，其 IC50 值分别为 9.59 和 11.32 ug/ml。

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Scillascillin Chemical Structure

Scillascillin Chemical Structure

CAS No. : 52706-07-7

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Scillascillin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Scillascillin (compound 10) is a homoisoflavanone. Scillascillin can be isolated from S. scilloides. Scillascillin shows anticancer activity towards MCF-7 (breast cancer) and DU-145 (prostate cancer) cells with the IC50 of 9.59 and 11.32 ug/ml, respectively[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HUVEC GI50
> 100 μM
Compound: 15
Antiproliferative activity against HUVEC assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
Antiproliferative activity against HUVEC assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
[PMID: 30951308]
Y79 GI50
> 100 μM
Compound: 15
Cytotoxicity against human Y79 cells assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
Cytotoxicity against human Y79 cells assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
[PMID: 30951308]
分子量

312.27

Formula

C17H12O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Scillascillin 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Scillascillin52706-07-7OthersFlavanonesMCF-7DU-145Inhibitorinhibitorinhibit

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