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  4. UHMCP1 dihydrochloride

UHMCP1 dihydrochloride 是一种有效的 UHM 结构域 剪接抑制剂，Kd 值为 79 µM。UHMCP1 dihydrochloride 可防止 SF3b155/U2AF65 相互作用。UHMCP1 dihydrochloride 影响细胞活力和 RNA 剪接。

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UHMCP1 dihydrochloride Chemical Structure

UHMCP1 dihydrochloride Chemical Structure

CAS No. : 2925647-93-2

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Other Forms of UHMCP1 dihydrochloride:

UHMCP1 dihydrochloride 相关抗体

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  • 生物活性

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生物活性

UHMCP1 dihydrochloride is a potent UHM domain splicing inhibitor with a Kd value of 79 µM. UHMCP1 dihydrochloride prevents the SF3b155/U2AF65 interaction. UHMCP1 dihydrochloride impacts cell viability and RNA splicing[1].

IC50 & Target

Kd: 79 µM (UHM domain)[1]
体外研究
(In Vitro)

UHMCP1 dihydrochloride (0-100 µM; 24 h) impacts cell viability and splicing with an EC50 value of 140 µM in HEK293 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

UHMCP1 dihydrochloride 相关抗体:

Cell Viability Assay[1]

Cell Line: HEK293 cells
Concentration: 0-100 µM
Incubation Time: 24 h
Result: Inhibited cell viability with an EC50 value of 140 µM.
分子量

370.36

Formula

C19H29Cl2N3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

UHMCP1 dihydrochloride 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

UHMCP12925647-93-2UHMCP 1UHMCP-1OthersHEK293 cellsRNA splicinganticancerU2AF65/SF3b155 interactionInhibitorinhibitorinhibit

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产品名称：
UHMCP1 dihydrochloride
目录号：
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