1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. UK-66914

UK-66914,是一种 III 类抗心律失常试剂,专门作用于延迟整流钾电流 (I_K)。UK-66914 旨在延长动作电位持续时间 (APD) 并增加心脏不应期,从而潜在地终止心律失常中的再入机制,而不影响与其他离子通道 (如Na+和Ca2+电流) 相关的抗心律失常药物的严重副作用。

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UK-66914 Chemical Structure

UK-66914 Chemical Structure

CAS No. : 113049-11-9

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生物活性

UK-66914, is a class III antiarrhythmic agent that specifically acts on the delayed rectifier potassium current (I_K). UK-66914 is designed to prolong action potential duration (APD) and increase cardiac refractory period, thereby potentially terminating the reentry mechanism in arrhythmias without affecting the serious side effects of antiarrhythmic drugs associated with other ion channels such as Na+ and Ca2+ currents[1].

分子量

376.47

Formula

C18H24N4O3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
UK-66914
目录号:
HY-118148
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