2. Cell Cycle/DNA Damage
  3. CDK
  4. Xylocydine

Xylocydine 是 CDK1/2 的抑制剂，抑制各种细胞凋亡过程中的 CDK 功能。Xylocydine 可特异性阻断 CDK1 和 CDK2 活性，IC50 分别为 1.4 nM 和 61 nM。此外，Xylocydine 还可下调磷酸化核仁素和视网膜母细胞瘤蛋白水平。

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Xylocydine Chemical Structure

Xylocydine Chemical Structure

CAS No. : 685901-63-7

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Xylocydine 相关抗体

Top Publications Citing Use of Products

查看 CDK 亚型特异性产品:

查看所有亚型
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • 生物活性

  • 纯度 & 产品资料

生物活性

Xylocydine is an inhibitor of CDK1/2, inhibiting CDK function in various apoptotic processes. Xylocydine specifically blocks CDK1 and CDK2 activity with IC50 of 1.4 nM and 61 nM, respectively. In addition, Xylocydine downregulates phosphorylated nucleolin and retinoblastoma protein levels.[1].

IC50 & Target

IC50: 1.4 nM (CDK1), 61 nM (CDK2)[1]
分子量

388.17

Formula

C12H14BrN5O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Xylocydine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Xylocydine685901-63-7CDKCyclin dependent kinaseInhibitorinhibitorinhibit

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