2. MAPK/ERK Pathway TGF-beta/Smad Stem Cell/Wnt
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  4. 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 

目录号: HY-142042
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3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 是骨形态发生蛋白 2 (BMP2) 的抑制剂，IC50 为 2.2 μM。3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 是丝裂原活化蛋白激酶 1 (MEK1) 的抑制剂。3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 在 EAE 小鼠模型中表现出抗炎和神经保护活性。

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3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles Chemical Structure

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles Chemical Structure

CAS No. : 287196-91-2

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规格 价格 是否有货 数量
5 mg ￥1400
1 - 2 周
10 mg ￥2250
1 - 2 周
25 mg ￥4500
1 - 2 周
50 mg ￥7200
1 - 2 周
100 mg   询价  
200 mg   询价  

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3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 相关抗体

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生物活性

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is an inhibitor for bone morphogenetic protein 2 (BMP2) with an IC50 of 2.2 μM. 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is inhibitor for mitogen-activated protein kinase 1 (MEK1). 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles exhibits anti-inflammatory and neuroprotective activity in EAE mouse model[1][2].

分子量

285.25

Formula

C11H6F3N3OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles287196-91-2MEKTGF-beta/SmadMitogen-activated protein kinase kinaseMAPKKMAP2KTransforming growth factor betaExperimental autoimmune encephalomyelitisEAEmultiple sclerosisInhibitorinhibitorinhibit

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