1. GPCR/G Protein Neuronal Signaling
  2. Melatonin Receptor 5-HT Receptor
  3. 7-Desmethyl-3-hydroxyagomelatine

7-Desmethyl-3-hydroxyagomelatine  (Synonyms: 3-Hydroxy-7-desmethyl agomelatine)

目录号: HY-133112
产品使用指南

7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine) 是 Agomelatine 的代谢产物。7-Desmethyl-3-hydroxyagomelatine 的活性低于 Agomelatine 。Agomelatine 是一种 melatonergic (MT1 and MT2) 激动剂和 serotonergic (5HT2C) 拮抗剂。

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7-Desmethyl-3-hydroxyagomelatine Chemical Structure

7-Desmethyl-3-hydroxyagomelatine Chemical Structure

CAS No. : 166527-00-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity than Agomelatine[1]. Agomelatine is a melatonergic (MT1 and MT2) agonist and serotonergic (5HT2C) antagonist[1][2].

IC50 & Target[1][2]

MT1

 

MT2

 

5-HT2C Receptor

 

分子量

245.27

Formula

C14H15NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
7-Desmethyl-3-hydroxyagomelatine
目录号:
HY-133112
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