2. Anti-infection
  3. CHIKV Flavivirus
  4. Anti-Chikungunya virus E2 Antibody (CHK-265)

Anti-Chikungunya virus E2 Antibody (CHK-265) 

目录号: HY-P990825
技术支持

Anti-Chikungunya virus E2 Antibody (CHK-265) 是小鼠源 IgG2c κ 型抗体抑制剂，靶向 Chikungunya virus E2。Anti-Chikungunya virus E2 Antibody (CHK-265) 与基孔肯雅病毒 E2 糖蛋白 B 结构域上的一个保守表位发生反应。Anti-Chikungunya virus E2 Antibody (CHK-265) 可阻断病毒的进入和释放。Anti-Chikungunya virus E2 Antibody (CHK-265) 可用于感染性疾病的研究，如基孔肯雅病毒 (CHIKV)、马亚罗病毒 (MAYV) 和奥尼昂尼昂病毒 (ONNV)。

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Anti-Chikungunya virus E2 Antibody (CHK-265)

Anti-Chikungunya virus E2 Antibody (CHK-265) Chemical Structure

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Anti-Chikungunya virus E2 Antibody (CHK-265) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Chikungunya virus E2 Antibody (CHK-265) is mouse-derived IgG2c κ type antibody inhibitor, targeting to Chikungunya virus E2. Anti-Chikungunya virus E2 Antibody (CHK-265) reacts with a conserved epitope on the B domain of the E2 glycoprotein of chikungunya virus. Anti-Chikungunya virus E2 Antibody (CHK-265) can block viral entry and egress. Anti-Chikungunya virus E2 Antibody (CHK-265) can be used for the research of infection, such as Chikungunya virus (CHIKV), Mayaro (MAYV) and O’nyong’nyong virus (ONNV)[1].

同型

Mouse IgG2c
推荐同型对照抗体
反应种属

Virus
IC50 & Target

B domain of the E2 glycoprotein of chikungunya virus
体外研究
(In Vitro)

Anti-Chikungunya virus E2 Antibody (CHK-265) (0.001-10 μg/mL, 19 h) 可中和与基孔肯雅病毒 (CHIKV) 亲缘关系近的甲病毒 (奥尼昂尼昂病毒，ONNV) 或远的 (马亚罗病毒，MAYV；罗斯河病毒，RRV；以及辛德毕斯病毒，SFV)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Chikungunya virus E2 Antibody (CHK-265) 相关抗体:
体内研究
(In Vivo)

Anti-Chikungunya virus E2 Antibody (CHK-265) (100 μg，腹腔注射，感染前 1 天给药) 可保护感染基孔肯雅病毒 (CHIKV)/马亚罗病毒 (MAYV)/奥尼昂尼昂病毒(ONNV) 的小鼠免受甲病毒疾病侵害[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CHIKV/MAYV/ONNV infected mice models[1]
Dosage: 100 μg
Administration: Intraperitoneally injection, 1 day prior to infection
Result: Reduced ankle joint swelling.
Reduced spread to the contralateral ankle joint.
Decreased viral burden.
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Chikungunya virus E2 Antibody (CHK-265) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Chikungunya virus E2 Antibody (CHK-265)CHIKVFlavivirusChikungunya virus AlphavirusesChikungunya virusMayaroO’nyong’nyong virusInhibitorinhibitorinhibit

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目录号：
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