2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 95

新型2-（喹啉-4-基氧基）乙酰胺类抗结核剂对结核分枝杆菌H37Rv参考菌株的最低抑制浓度（MIC）值低至0.3μM，并且抑制了结核病感染巨噬细胞模型中结核分枝杆菌的生长。

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Antibacterial agent 95 Chemical Structure

Antibacterial agent 95 Chemical Structure

CAS No. : 2413006-48-9

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Antibacterial agent 95 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

The minimum inhibitory concentration (MIC) of a new 2- (quinoline-4-methoxy) acetamide antituberculotic agent against the reference strain of Mycobacterium tuberculosis H37Rv was as low as 0.3 μ M. It also inhibited the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 CC50
> 20 μM
Compound: 3h
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 32113048]
HepG2 CC50
> 20 μM
Compound: 3h
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
[PMID: 32113048]
Vero CC50
> 20 μM
Compound: 3h
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 32113048]
Vero CC50
> 20 μM
Compound: 3h
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
[PMID: 32113048]
分子量

341.79

Formula

C19H16ClNO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 95 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 952413006-48-9Antibacterial agent95Antibacterial agent-95BacterialInhibitorinhibitorinhibit

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