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  4. Asterric Acid

Asterric Acid  (Synonyms: Dimethylosoic acid; RES-1214-1; TAN 1415A)

目录号: HY-119843
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摩尔计算器

Asterric Acid (Dimethylosoic acid; RES-1214-1)是一种抗生素真菌代谢物，它在 0.1 μM 时可完全抑制强效血管收缩剂内皮素 (ET)-1 与 A10 细胞中的 ETA 受体结合。Asterric Acid (Dimethylosoic acid; RES-1214-1)衍生物还被证实可在 3-10 μM 时抑制 VEGF 诱导的人脐静脉内皮细胞管道形成，这表明它可用作抗血管生成剂。

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Asterric Acid Chemical Structure

Asterric Acid Chemical Structure

CAS No. : 577-64-0

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Asterric Acid 相关抗体

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  • 生物活性

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生物活性

Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 μM.1 Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 μM, which suggests its usefulness as an antiangiogenic agent.

分子量

348.30

Formula

C17H16O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Asterric Acid 相关分类

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Keywords:

Asterric Acid577-64-0Dimethylosoic acid RES-1214-1 TAN 1415AOthersInhibitorinhibitorinhibit

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