2. Neuronal Signaling
  3. AAK1
  4. BMS-901715

BMS-901715 是一种有效的，选择性的衔接蛋白-2 相关激酶 1 (AAK1) 抑制剂，IC50 为 3.3 nM。

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BMS-901715 Chemical Structure

BMS-901715 Chemical Structure

CAS No. : 1699861-37-4

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BMS-901715 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BMS-901715 is a potent and selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 of 3.3 nM[1][2].

IC50 & Target

IC50: 3.3 nM (Adapter protein-2 associated kinase 1 (AAK1))[2]
体外研究
(In Vitro)

Adaptor associated kinase 1 (AAK1) is a member of the Ark1/Prk1 family of serine/threonine kinases. AAK1 mRNA exists in two splice forms termed short and long. The long form predominates and is highly expressed in brain and heart. AAK1 is enriched in synaptosomal preparations and is co-localized with endocytic structures in cultured cells. AAK1 modulates clatherin coated endocytosis, a process that is important in synaptic vesicle recycling and receptor-mediated endocytosis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BMS-901715 相关抗体:
分子量

448.52

Formula

C22H28N10O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BMS-901715 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-9017151699861-37-4BMS901715BMS 901715AAK1Adaptor-associated Kinase 1AP2-associated kinase 1potentInhibitorinhibitorinhibit

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