2. Metabolic Enzyme/Protease
  3. Tyrosinase Endogenous Metabolite
  4. Cepharadione B

Cepharadione B (compound 22) 是从胡椒叶中分离得到的天然化合物。Cepharadione B 是一种 tyrosinase 抑制剂，其 < B >IC50值为170 μM, 抑制 A-549、SK-OV-3、SK-MEL-2、XF-498 和 HCT-15 细胞的生长。

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Cepharadione B Chemical Structure

Cepharadione B Chemical Structure

CAS No. : 55610-02-1

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规格 价格 是否有货
1 mg ￥4100
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Cepharadione B 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cepharadione B (compound 22) is a natural compound isolated from the leaves of Piper sanctum. Cepharadione B is a tyrosinase inhibitor with an IC50 value of 170 μM, and inhibits cell growth in A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cells[1][2][3].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BXPC-3 GI50
> 10 μg/mL
Compound: 1
Growth inhibition of human BXPC3 cells after 48 hrs by SRB assay
Growth inhibition of human BXPC3 cells after 48 hrs by SRB assay
[PMID: 17624787]
DU-145 GI50
36.1 μg/mL
Compound: 1
Growth inhibition of human DU145 cells after 48 hrs by SRB assay
Growth inhibition of human DU145 cells after 48 hrs by SRB assay
[PMID: 17624787]
KM-20L2 GI50
> 10 μg/mL
Compound: 1
Growth inhibition of human KM20L2 cells after 48 hrs by SRB assay
Growth inhibition of human KM20L2 cells after 48 hrs by SRB assay
[PMID: 17624787]
MCF7 GI50
> 10 μg/mL
Compound: 1
Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
[PMID: 17624787]
NCI-H460 GI50
> 10 μg/mL
Compound: 1
Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
[PMID: 17624787]
SF-268 GI50
22.8 μg/mL
Compound: 1
Growth inhibition of human SF268 cells after 48 hrs by SRB assay
Growth inhibition of human SF268 cells after 48 hrs by SRB assay
[PMID: 17624787]
分子量

321.33

Formula

C19H15NO4
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cepharadione B 相关分类

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cepharadione B55610-02-1TyrosinaseEndogenous MetaboliteCepharadione B (compound 22) 是从胡椒叶中分离得到的天然化合物。Cepharadione B 是一种 tyrosinase 抑制剂，其 < B >IC50值为170 μM抑制 A-549、SK-OV-3、SK-MEL-2、XF-498 和 HCT-15 细胞的生长。Inhibitorinhibitorinhibit

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