1. Others Anti-infection
  2. Isotope-Labeled Compounds Influenza Virus Parasite
  3. Cletoquine-d4-1

Cletoquine-d4-1  (Synonyms: 克尼托喹-d4; Desethylhydroxychloroquine-d4-1)

目录号: HY-135810S1
产品使用指南

Cletoquine-d4-1 是 Cletoquine 的氘代物。Cletoquine (Desethylhydroxychloroquine) 是 Hydroxychloroquine 的主要活性代谢产物,是由 CYP2D6,CYP3A4,CYP3A5 和 CYP2C8 同工酶在肝脏中形成的。Cletoquine 也是一种 Chloroquine 衍生物,具有抗基孔肯雅热病毒 (CHIKV) 的能力。Cletoquine

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Cletoquine-d<sub>4</sub>-1 Chemical Structure

Cletoquine-d4-1 Chemical Structure

CAS No. : 1216461-56-1

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规格 价格 是否有货 数量
500 μg 现货 询价
5 mg 询价
10 mg   询价  
50 mg   询价  

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Customer Review

Other Forms of Cletoquine-d4-1:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cletoquine-d4-1 is the deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

311.84

Formula

C16H18D4ClN3O

CAS 号
非标记 CAS

4298-15-1

中文名称

羟氯喹EP杂质C (Desethyl Hydroxy Chloroquine)-d4-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cletoquine-d4-1
目录号:
HY-135810S1
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