2. Immunology/Inflammation Neuronal Signaling
  3. COX Cholinesterase (ChE) Beta-secretase
  4. COX-2-IN-22

COX-2-IN-22 (Compound 4h) 是一种 COX-2 抑制剂，IC50 为 8.6 µM。COX-2-IN-22 也抑制AChE、BChE、β-Secretase、LOX-5 和 DPPH，IC50 值分别为 2.8、6.3,、15.3、 13.9 和 6.8 µM。COX-2-IN-22 能通过血脑屏障。

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COX-2-IN-22 Chemical Structure

COX-2-IN-22 Chemical Structure

CAS No. : 2447589-08-2

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规格 是否有货
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Customer Review

COX-2-IN-22 相关抗体

Top Publications Citing Use of Products

查看 COX 亚型特异性产品:

查看所有亚型
COX COX-1 COX-2 COX-3

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

查看 Beta-secretase 亚型特异性产品:

查看所有亚型
BACE1 BACE2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

COX-2-IN-22 (Compound 4h) is a COX-2 inhibitor with an IC50 of 8.6 µM. COX-2-IN-22 also inhibits AChE, BChE, β-Secretase, LOX-5 and DPPH with IC50 values of 2.8, 6.3, 15.3, 13.9 and 6.8 µM, respectively. COX-2-IN-22 can cross BBB[1].

IC50 & Target

COX-2

8.6 μM (IC50)

AChE

2.8 μM (IC50)

BChE

6.3 μM (IC50)

β-Secretase

15.3 μM (IC50)

LOX-5

13.9 μM (IC50)

DPPH

6.8 μM (IC50)

分子量

484.50

Formula

C29H24O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

COX-2-IN-22 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COX-2-IN-222447589-08-2COXCholinesterase (ChE)Beta-secretaseCyclooxygenaseBACEβ-SecretaseAlzheimer’s diseaseBBBanti-inflammatoryInhibitorinhibitorinhibit

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目录号：
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