2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. DDO-02005 free base

DDO-02005 (free base) 是一种有效的 Kv1.5 钙离子通道抑制剂，IC50 为 0.72 μM。DDO-02005 (free base) 在CaCl2-ACh 房颤大鼠模型中具有良好的抗房颤作用，并能有效抵抗乌头碱引起的心律失常。

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DDO-02005 free base Chemical Structure

DDO-02005 free base Chemical Structure

CAS No. : 1186134-30-4

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Other Forms of DDO-02005 free base:

DDO-02005 free base 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DDO-02005 (free base) is a potent Kv1.5 potassium channel inhibitor with an IC50 value of 0.72 μM. DDO-02005 (free base) has good anti-atrial fibrillation (AF) effect in CaCl2-ACh AF rats model and effective anti-arrhythmic activity caused by aconitine[1].

IC50 & Target

IC50: 0.72 μM (Kv1.5 potassium channel)[1]
分子量

351.44

Formula

C21H25N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DDO-02005 free base 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DDO-020051186134-30-4DDO02005DDO 02005Potassium ChannelKcsAKv1.5Anti-arrhythmicAtrial fibrillationSD ratsAconitineInhibitorinhibitorinhibit

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产品名称：
DDO-02005 free base
目录号：
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