2. Anti-infection
  3. Parasite
  4. Diacetylcercosporin

Diacetylcercosporin 是由尾孢菌和壳针孢菌产生的一种具有多种生物活性的苝醌。Diacetylcercosporin 可抑制对氯喹敏感和有抗性的恶性疟原虫菌株（D6 和 W2 克隆的 IC50s 分别为 2.75 和 1.94 μM）和利斯特氏菌寄生虫（IC50=3.1 μM）的体外生长。Diacetylcercosporin对 SK-MEL、KB、BT549 和 SKOV3 人类癌细胞系具有细胞毒性（IC50s=4.8-8.7 μM）。Diacetylcercosporin 也是一种植物毒素，在浓度为 1.62 mM 时可抑制莴苣和翦股颖的生长。

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Diacetylcercosporin Chemical Structure

Diacetylcercosporin Chemical Structure

CAS No. : 62574-06-5

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Diacetylcercosporin 相关抗体

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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生物活性

Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities. Diacetylcercosporin inhibits the growth of P. falciparum strains that are sensitive and resistant to chloroquine (IC50s=2.75 and 1.94 μM for D6 and W2 clones, respectively) and L. donovani parasites (IC50=3.1 μM) in vitro. Diacetylcercosporin exhibits cytotoxicity against SK-MEL, KB, BT549, and SKOV3 human cancer cell lines (IC50s=4.8-8.7 μM). Diacetylcercosporin is also a phytotoxin that inhibits the growth of lettuce and bentgrass at a concentration of 1.62 mM.

分子量

618.58

Formula

C33H30O12
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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Diacetylcercosporin 相关分类

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Keywords:

Diacetylcercosporin62574-06-5ParasiteInhibitorinhibitorinhibit

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