2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. Estrogen receptor antagonist 7

Estrogen receptor antagonist 7 

目录号: HY-143253
产品使用指南

摩尔计算器

Estrogen receptor antagonist 7 (compound 13) 是一种有效的雌激素受体 (ER) 拮抗剂。Estrogen receptor antagonist 7 可抑制乳腺癌细胞和卵巢癌细胞的生长，具有抗癌活性和抗子宫营养活性。

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Estrogen receptor antagonist 7 Chemical Structure

Estrogen receptor antagonist 7 Chemical Structure

CAS No. : 2889371-04-2

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Estrogen receptor antagonist 7 相关抗体

Top Publications Citing Use of Products

查看 Estrogen Receptor/ERR 亚型特异性产品:

查看所有亚型
Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Estrogen receptor antagonist 7 (compound 13) is a potent estrogen receptors (ER) antagonist. Estrogen receptor antagonist 7 has antiproliferative activity against breast and ovarian cancer cells. Anticancer and anti-uterotrophic activities[1].

IC50 & Target

IC50: 7.2 µM in MCF-7, 11.71 µM in T-47D, 29.8 µM in SKOV-3[1]
体外研究
(In Vitro)

Estrogen receptor antagonist 7 (compound 13) has antiproliferative activity against MCF-7, T-47D and SKOV-3 with IC50s of 7.2 µM, 11.71 µM and 29.8 µM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Estrogen receptor antagonist 7 相关抗体:
分子量

399.40

Formula

C23H17N3O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Estrogen receptor antagonist 7 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estrogen receptor antagonist 72889371-04-2Estrogen receptor antagonist7Estrogen receptor antagonist-7Estrogen Receptor/ERRBreast cancerovarian cancerMCF-7T-47DSKOV-3antiproliferativeanticanceranti-uterotrophicInhibitorinhibitorinhibit

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