2. JAK/STAT Signaling Stem Cell/Wnt
  3. STAT
  4. Eucannabinolide

Eucannabinolide  (Synonyms: Hiyodorilactone A; Schkuhrin I)

目录号: HY-118618
产品使用指南

摩尔计算器

Eucannabinolide 是 STAT3 的抑制剂。Eucannabinolide 抑制 STAT3 在酪氨酸705位点的激活，抑制其向细胞核的易位，降低其 DNA 结合能力。Eucannabinolide 可用于三阴性乳腺癌的研究。 (1-OH)-Exatecan 是一种喹啉环化合物，(1-OH)-Exatecan 具有实质性的抗增殖作用，可用于癌症疾病的研究。

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Eucannabinolide Chemical Structure

Eucannabinolide Chemical Structure

CAS No. : 38458-58-1

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Eucannabinolide 相关抗体

Top Publications Citing Use of Products

查看 STAT 亚型特异性产品:

查看所有亚型
STAT3 STAT5 STAT6 STAT1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eucannabinolide is a STAT3 inhibitor. Eucannabinolide suppresses STAT3 activation at tyrosine 705, inhibiteds its translocation to nucleus, and decreases its DNA binding capacity. Eucannabinolide can be used for triple negative breast cancer (TNBC) diseases research[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
L6 IC50
7.8 μM
Compound: 8
Cytotoxicity against rat L6 cells after 72 hrs by alamar blue staining based fluorescence assay
Cytotoxicity against rat L6 cells after 72 hrs by alamar blue staining based fluorescence assay
[PMID: 29244495]
分子量

420.45

Formula

C22H28O8
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Eucannabinolide 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eucannabinolide38458-58-1Hiyodorilactone A Schkuhrin ISTATcancerTNBCSTAT3Inhibitorinhibitorinhibit

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