2. 天然产物
  3. 疾病研究领域 酚类 微生物
  4. 癌症 单酚类
  5. Eupenifeldin

Eupenifeldin 是从 Eupenicillium brefeldianum ATCC 74184 培养物中分离出的五环双酚酮。Eupenifeldin 对 HCT-116 细胞系具有细胞毒性。Eupenifeldin 具有研究白血病的潜力。

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Eupenifeldin Chemical Structure

Eupenifeldin Chemical Structure

CAS No. : 151803-45-1

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规格 价格 是否有货 数量
100 μg ￥5119
3 - 4 周
100 μg 询价
500 μg 询价

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Eupenifeldin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eupenifeldin is pentacyclic bistropolone isolated from cultures of Eupenicillium brefeldianum ATCC 74184. Eupenifeldin is cytotoxic against the HCT-116 cell line. Eupenifeldin has the potential for the research of leukemia[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
30.6 nM
Compound: 4
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
[PMID: 26651221]
H4 IC50
130 nM
Compound: 4
Antiproliferative activity against human H4 cells after 48 hrs by MTT assay
Antiproliferative activity against human H4 cells after 48 hrs by MTT assay
[PMID: 26651221]
HCT-116 IC50
31.2 nM
Compound: 4
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
[PMID: 26651221]
HeLa IC50
8.2 nM
Compound: 4
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
[PMID: 26651221]
SH-SY5Y IC50
80 nM
Compound: 4
Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay
Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay
[PMID: 26651221]
T-24 IC50
12.5 nM
Compound: 4
Antiproliferative activity against human T24 cells after 48 hrs by MTT assay
Antiproliferative activity against human T24 cells after 48 hrs by MTT assay
[PMID: 26651221]
U-251 IC50
100 nM
Compound: 4
Antiproliferative activity against human U251 cells after 48 hrs by MTT assay
Antiproliferative activity against human U251 cells after 48 hrs by MTT assay
[PMID: 26651221]
分子量

548.67

Formula

C33H40O7
CAS 号
结构分类
初始来源

Eupenicillium brefeldianum
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Eupenifeldin 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eupenifeldin151803-45-1OthersEupenicillium brefeldianumcytotoxicleukemiaInhibitorinhibitorinhibit

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