SYNCRIP - synaptotagmin binding cytoplasmic RNA interacting protein Gene

中文名称：突触结合蛋白结合细胞质 RNA 相互作用蛋白

种属: Homo sapiens

同用名: PP68; NSAP1; GRYRBP; HNRNPQ; HNRPQ1; GRY-RBP; hnRNP-Q

关于 SYNCRIP

功能概要

该基因编码细胞异质核核糖核蛋白 (hnRNP) 家族的成员。 hnRNPs 是 RNA 结合蛋白，与异质核 RNA (hnRNA) 复合并调节选择性剪接、聚腺苷酸化以及 mRNA 代谢和运输的其他方面。编码的蛋白质在 mRNA 成熟的多个方面发挥作用，并与几种多蛋白复合物相关，包括 apoB RNA 编辑复合物和运动神经元存活 (SMN) 复合物。已经观察到该基因编码多种亚型的可变剪接转录变体，并且该基因的假基因位于 20 号染色体的短臂上。[RefSeq 提供，2011 年 12 月]

This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and Other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011]