MRPL28 - mitochondrial ribosomal protein L28 Gene

中文名称：线粒体核糖体蛋白 L28

种属: Homo sapiens

同用名: p15; MAAT1

关于 MRPL28

功能概要

哺乳动物线粒体核糖体蛋白由核基因编码，有助于线粒体内的蛋白质合成。线粒体核糖体 (线粒体核糖体) 由一个小的 28S 亚基和一个大的 39S 亚基组成。与原核核糖体相比，它们估计有 75% 的蛋白质与 rRNA 组成，而原核核糖体的比例是相反的。哺乳动物 线粒体核糖体 和原核核糖体之间的另一个区别是后者包含 5S rRNA。在不同的物种中，构成核糖体的蛋白质在序列上有很大差异，有时在生化特性上也有很大差异，这使得序列同源性难以识别。该基因编码一个 39S 亚基蛋白，其中一部分最初是通过其以 HLA-A24 限制性方式识别酪氨酸酶的能力而被分离出来的。[RefSeq 提供，2008 年 7 月]

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize Tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008]