2. Gene
  3. YKT6 - YKT6 v-SNARE homolog Gene

YKT6 - YKT6 v-SNARE homolog Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：YKT6 v-SNARE 同系物

种属: Homo sapiens

基因 ID: 10652 | 基因类型: protein coding

关于 YKT6

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:44,200,978-44,214,294 (from NCBI)

This gene has 15 transcripts (splice variants), 232 orthologues and 10 paralogues. Ubiquitous expression in brain (RPKM 24.8), colon (RPKM 21.7) and 25 other tissues.

功能概要

该基因产物是涉及分泌区室之间囊泡转运的 SNARE 识别分子之一。它是一种膜相关的异戊二烯化蛋白质，在内质网-高尔基体转运步骤中发挥作用。这种蛋白质从酵母到人类高度保守，可以在功能上补充酵母分泌途径中酵母同系物的缺失。[RefSeq 提供，2008 年 7 月]

This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. [provided by RefSeq, Jul 2008]

YKT6 基因产物(3)

mRNA Protein Name
NM_001363678.2 NP_001350607.1 synaptobrevin homolog YKT6 isoform 2
NM_001410874.1 NP_001397803.1 synaptobrevin homolog YKT6 isoform 3
NM_006555.4 NP_006546.1 synaptobrevin homolog YKT6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SNAP receptor activity IDA
IDA: 通过直接分析推断
15215310 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
33422265 GOA
enables protein-cysteine S-palmitoyltransferase activity IDA
IDA: 通过直接分析推断
15479160 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endoplasmic reticulum to Golgi vesicle-mediated transport IDA
IDA: 通过直接分析推断
9211930 GOA
involved in retrograde transport, endosome to Golgi IDA
IDA: 通过直接分析推断
15215310 GOA
involved in vesicle docking involved in exocytosis IDA
IDA: 通过直接分析推断
9211930 GOA
involved in vesicle targeting IDA
IDA: 通过直接分析推断
9211930 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
15215310 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
25468996 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
9211930 GOA
located in endosome IDA
IDA: 通过直接分析推断
15215310 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
9211930 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

YKT6 蛋白结构

Longin

Longin: Regulated-SNARE-like domain (44 - 106)

Synaptobrevin

Synaptobrevin: Synaptobrevin (136 - 192)

  • 0
  • 100
  • 198 a.a.
蛋白主名 其他名称

synaptobrevin homolog YKT6

R-SNARE

重组 YKT6 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71025 YKT6 Protein, Human (His) O15498-1 (M1-M198) ≥95%

关联疾病

疾病名称 别名
Foodborne Botulism

Botulism

Botulism Poisoning

Intoxication With Clostridium Botulinum Toxin

Wound Botulism

Food Poisoning Due To Clostridium Botulinum

Infection Due To Clostridium Botulinum

Infant Botulism

Intoxication Botulism

Botulism, Infantile

Clostridium Botulinum Poisoning

Botulism Nos
Infant Botulism

Infant Intestinal Botulism

Infant Intestinal Toxemia Botulism

Infant Intestinal Toxin-Mediated Botulism

Infantile Botulism

Botulism, Infantile
Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome

Cednik Syndrome

CEDNIK

Cerebral Dysgenesis, Neuropathy, Ichthyosis And Keratoderma Syndrome

Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndro

Cerebral Dysgenesis-Neuropathy-Ichthyosis-Palmoplantar Keratoderma Syndrome

Cerebral Dysgenesis-Neuropathy-Ichthyosis-Keratoderma Syndrome

Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma

Neurocutaneous Syndromes
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15927 YKT6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus YKT6 VGNC VGNC:37030
Mus musculus YKT6 MGD MGI:1927550
Macaca mulatta YKT6 VGNC VGNC:81796
Felis catus YKT6 VGNC VGNC:67146
Rattus norvegicus YKT6 RGD RGD:70897
Others YKT6 NCBI
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