2. Gene
  3. ESM1 - endothelial cell specific molecule 1 Gene

ESM1 - endothelial cell specific molecule 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：内皮细胞特异性分子 1

种属: Homo sapiens

同用名: endocan

基因 ID: 11082 | 基因类型: protein coding

关于 ESM1

Cytogenetic location: 5q11.2 Genomic coordinates (GRCh38): 5:54,977,867-54,985,593 (from NCBI)

This gene has 4 transcripts (splice variants) and 196 orthologues. Biased expression in thyroid (RPKM 12.6), kidney (RPKM 8.9) and 9 other tissues.

功能概要

该基因编码一种分泌蛋白，主要在人肺和肾组织的内皮细胞中表达。该基因的表达受细胞因子调节，表明它可能在内皮依赖性病理障碍中发挥作用。转录物包含多个聚腺苷酸化和 mRNA 不稳定信号。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供，2008 年 10 月]

This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

ESM1 基因产物(2)

mRNA Protein Name
NM_001135604.2 NP_001129076.1 endothelial cell-specific molecule 1 isoform b precursor
NM_007036.5 NP_008967.1 endothelial cell-specific molecule 1 isoform a precursor

ESM1 蛋白结构

IGFBP

IGFBP: Insulin-like growth factor binding protein (28 - 83)

  • 0
  • 100
  • 184 a.a.
蛋白主名 其他名称

endothelial cell-specific molecule 1

ESM-1

重组 ESM1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70151 ESM-1 Protein, Human (HEK293, His) AAH11989.1/Q9NQ30-1 (W20-R184 ) ≥95%
HY-P75219 ESM-1 Protein, Human (sf9, His) Q9NQ30/NP_008967.1 (M1-R184) ≥95%

关联疾病

疾病名称 别名
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04526 ESM1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ESM1 VGNC VGNC:40474
Bos taurus ESM1 VGNC VGNC:28602
Mus musculus ESM1 MGD MGI:1918940
Macaca mulatta ESM1 VGNC VGNC:72431
Rattus norvegicus ESM1 RGD RGD:71013
Felis catus ESM1 VGNC VGNC:61962
Others ESM1 NCBI
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