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  2. Ccl4 - C-C motif chemokine ligand 4 Gene

Ccl4 - C-C motif chemokine ligand 4 Gene

种属: Rattus norvegicus

同用名: Scya4; Mip1-b

基因 ID: 116637 | 基因类型: protein coding

关于 Ccl4

功能概要

Enables chemokine activity. Involved in several processes, including leukocyte chemotaxis; positive regulation of tumor necrosis factor production; and positive regulation of vascular permeability. Predicted to be active in extracellular space. Biomarker of anti-basement membrane glomerulonephritis; obesity; and status epilepticus. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL4L2 (C-C motif chemokine ligand 4 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Ccl4 基因产物(1)

mRNA Protein Name
NM_053858.2 NP_446310.2 C-C motif chemokine 4 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemokine activity IDA
IDA: 通过直接分析推断
10679105 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in leukocyte chemotaxis IDA
IDA: 通过直接分析推断
10679105 RGD
involved in positive regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
10679105 RGD
involved in positive regulation of vascular permeability IDA
IDA: 通过直接分析推断
10679105 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

C-C motif chemokine 4

MIP-1-beta

chemokine (C-C motif) ligand 4

macrophage inflammatory protein 1-beta

small-inducible cytokine A4

重组 Ccl4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71899 CCL4 Protein, Rat P50230 (A24-N92) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccl4 NCBI NCBI:6351
Mus musculus Ccl4 NCBI NCBI:20303