2. Gene
  3. Efnb2 - ephrin B2 Gene

Efnb2 - ephrin B2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Epl5; ELF-2; Eplg5; Htk-L; Lerk5; LERK-5; NLERK-1

基因 ID: 13642 | 基因类型: protein coding

关于 Efnb2

功能概要

Enables signaling receptor binding activity. Involved in several processes, including adherens junction organization; positive regulation of cardiac muscle cell differentiation; and regulation of postsynaptic neurotransmitter receptor internalization. Acts upstream of or within several processes, including negative regulation of keratinocyte proliferation; positive regulation of aorta morphogenesis; and vasculature development. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and plasma membrane. Is integral component of postsynaptic density membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; sensory organ; and urinary system. Orthologous to human EFNB2 (Ephrin B2). [provided by Alliance of Genome Resources, Apr 2022]

Efnb2 基因产物(2)

mRNA Protein Name
NM_001368299.1 NP_001355228.1 ephrin-B2 isoform 2
NM_010111.6 NP_034241.2 ephrin-B2 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16511561 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
11780069 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell costimulation IDA
IDA: 通过直接分析推断
15599401 MGI
involved in adherens junction organization IDA
IDA: 通过直接分析推断
30639848 MGI
acts upstream of or within animal organ morphogenesis IMP
IMP: 通过突变表型推断
15223334 MGI
acts upstream of or within blood vessel morphogenesis IMP
IMP: 通过突变表型推断
19571816 MGI
acts upstream of keratinocyte proliferation IMP
IMP: 通过突变表型推断
19571816 MGI
acts upstream of or within lymph vessel development IMP
IMP: 通过突变表型推断
15687262 MGI
acts upstream of or within negative regulation of keratinocyte proliferation IMP
IMP: 通过突变表型推断
19571816 MGI
acts upstream of or within nephric duct morphogenesis IMP
IMP: 通过突变表型推断
25139858 MGI
acts upstream of or within positive regulation of aorta morphogenesis IMP
IMP: 通过突变表型推断
18952909 MGI
involved in positive regulation of cardiac muscle cell differentiation IMP
IMP: 通过突变表型推断
17336907 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: 通过直接分析推断
11754836 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: 通过突变表型推断
11754836 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: 通过直接分析推断
19160501 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IEP
IEP: 通过表达模式推断
19160501 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: 通过突变表型推断
19160501 MGI
acts upstream of or within venous blood vessel morphogenesis IMP
IMP: 通过突变表型推断
18952909 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
11754836 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
11754836 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
11754836 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
19160501 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
11754836 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15223334 MGI
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
14699416 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ephrin-B2

EPH-related receptor tyrosine kinase ligand 5

HTK ligand

重组 Efnb2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70378 Ephrin-B2/EFNB2 Protein, Mouse (HEK293, Fc-His) P52800 (R29-E227) ≥95%
HY-P73017 Ephrin-B2/EFNB2 Protein, Mouse (HEK293, Fc) P52800/NP_034241.2 (R29-A232) ≥95%
HY-P73018 Ephrin-B2/EFNB2 Protein, Mouse (HEK293, His) P52800 (R29-A232) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04198 EFNB2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Efnb2 NCBI NCBI:1948
Canis familiaris Efnb2 NCBI NCBI:611745
Rattus norvegicus Efnb2 NCBI NCBI:306636
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