RNF183 - ring finger protein 183 Gene

中文名称：无名指蛋白 183

种属: Homo sapiens

基因 ID: 138065 | 基因类型: protein coding

关于 RNF183

This gene has 7 transcripts (splice variants), 92 orthologues and 3 paralogues. Biased expression in gall bladder (RPKM 1.5), kidney (RPKM 1.3) and 7 other tissues.

功能概要

启用泛素蛋白连接酶活性。参与内质网应激诱导的内在凋亡信号通路的正调控；蛋白质泛素化；和对内质网应激的反应。位于内质网。是内质网膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables ubiquitin protein Ligase activity. Involved in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; protein ubiquitination; and response to endoplasmic reticulum stress. Located in endoplasmic reticulum. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNF183 基因产物(7)

mRNA	Protein	Name
NM_001371234.1	NP_001358163.1	E3 ubiquitin-protein ligase RNF183
NM_001371235.1	NP_001358164.1	E3 ubiquitin-protein ligase RNF183
NM_001371236.1	NP_001358165.1	E3 ubiquitin-protein ligase RNF183
NM_001371237.1	NP_001358166.1	E3 ubiquitin-protein ligase RNF183
NM_001387568.1	NP_001374497.1	E3 ubiquitin-protein ligase RNF183
NM_001387569.1	NP_001374498.1	E3 ubiquitin-protein ligase RNF183
NM_145051.5	NP_659488.2	E3 ubiquitin-protein ligase RNF183

RNF183 蛋白结构

zf-RING_5

0
100
192 a.a.

蛋白主名

其他名称

E3 ubiquitin-protein ligase RNF183

probable E3 ubiquitin-protein ligase RNF183

RNF183 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	RNF183	Q96D59	UBE2W	Homo sapiens	Q96FI0	Y2H Prey Pooling	32296183
Intra	RNF183	Q96D59	UBE2W	Homo sapiens	Q96FI0	Validated Y2H	32296183
Intra	RNF183	Q96D59	UBE2W	Homo sapiens	Q96FI0	Y2H Array	32296183
Intra	RNF183	Q96D59	GTF3C3	Homo sapiens	Q9Y5Q9	Y2H Pooling	32814053
Intra	RNF183	Q96D59	GTF3C3	Homo sapiens	Q9Y5Q9	Validated Y2H	32814053
Intra	RNF183	Q96D59	GTF3C3	Homo sapiens	Q9Y5Q9	Y2H Array	32814053
Intra	RNF183	Q96D59	DNM2	Homo sapiens	P50570-2	Validated Y2H	32814053
Intra	RNF183	Q96D59	DNM2	Homo sapiens	P50570-2	Y2H Pooling	32814053
Intra	RNF183	Q96D59	DNM2	Homo sapiens	P50570-2	Y2H Array	32814053
Intra	RNF183	Q96D59	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
Intra	RNF183	Q96D59	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
Intra	RNF183	Q96D59	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
Intra	RNF183	Q96D59	GOPC	Homo sapiens	Q9HD26-2	Y2H Prey Pooling	32296183
Intra	RNF183	Q96D59	GOPC	Homo sapiens	Q9HD26-2	Validated Y2H	32296183
Intra	RNF183	Q96D59	GOPC	Homo sapiens	Q9HD26-2	Y2H Array	32296183
Intra	RNF183	Q96D59	MECP2	Homo sapiens	P51608	Y2H Pooling	32814053
Intra	RNF183	Q96D59	MECP2	Homo sapiens	P51608	Validated Y2H	32814053
Intra	RNF183	Q96D59	MECP2	Homo sapiens	P51608	Y2H Array	32814053
Intra	RNF183	Q96D59	ERCC8	Homo sapiens	Q13216-2	Validated Y2H	32814053
Intra	RNF183	Q96D59	ERCC8	Homo sapiens	Q13216-2	Y2H Array	32814053
Intra	RNF183	Q96D59	ERCC8	Homo sapiens	Q13216-2	Y2H Pooling	32814053
Intra	RNF183	Q96D59	GLE1	Homo sapiens	Q53GS7	Validated Y2H	32814053
Intra	RNF183	Q96D59	GLE1	Homo sapiens	Q53GS7	Y2H Pooling	32814053
Intra	RNF183	Q96D59	GLE1	Homo sapiens	Q53GS7	Y2H Array	32814053
Intra	RNF183	Q96D59	APBB2	Homo sapiens	Q92870-2	Validated Y2H	32814053
Intra	RNF183	Q96D59	APBB2	Homo sapiens	Q92870-2	Y2H Pooling	32814053
Intra	RNF183	Q96D59	APBB2	Homo sapiens	Q92870-2	Y2H Array	32814053
Intra	RNF183	Q96D59	DCTN1	Homo sapiens	Q14203-5	Validated Y2H	32814053
Intra	RNF183	Q96D59	DCTN1	Homo sapiens	Q14203-5	Y2H Array	32814053
Intra	RNF183	Q96D59	DCTN1	Homo sapiens	Q14203-5	Y2H Pooling	32814053
Intra	RNF183	Q96D59	q9p1n4_human	Homo sapiens	Q9P1N4	Y2H Array	32814053
Intra	RNF183	Q96D59	q9p1n4_human	Homo sapiens	Q9P1N4	Y2H Pooling	32814053
Intra	RNF183	Q96D59	q9p1n4_human	Homo sapiens	Q9P1N4	Validated Y2H	32814053
Intra	RNF183	Q96D59	TPP1	Homo sapiens	O14773	Validated Y2H	32814053
Intra	RNF183	Q96D59	TPP1	Homo sapiens	O14773	Y2H Array	32814053
Intra	RNF183	Q96D59	TPP1	Homo sapiens	O14773	Y2H Pooling	32814053
Intra	RNF183	Q96D59	GOPC	Homo sapiens	Q9HD26	Validated Y2H	25416956
Intra	RNF183	Q96D59	GOPC	Homo sapiens	Q9HD26	Y2H Array	25416956
Intra	RNF183	Q96D59	HSPB1	Homo sapiens	P04792	Validated Y2H	32814053
Intra	RNF183	Q96D59	HSPB1	Homo sapiens	P04792	Y2H Array	32814053
Intra	RNF183	Q96D59	HSPB1	Homo sapiens	P04792	Y2H Pooling	32814053
Intra	RNF183	Q96D59	RNF11	Homo sapiens	Q9Y3C5	Y2H Pooling	32814053
Intra	RNF183	Q96D59	RNF11	Homo sapiens	Q9Y3C5	Validated Y2H	32814053
Intra	RNF183	Q96D59	RNF11	Homo sapiens	Q9Y3C5	Y2H Array	32814053
Intra	RNF183	Q96D59	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
Intra	RNF183	Q96D59	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
Intra	RNF183	Q96D59	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
Intra	RNF183	Q96D59	HTRA2	Homo sapiens	O43464	Y2H Array	32814053
Intra	RNF183	Q96D59	HTRA2	Homo sapiens	O43464	Y2H Pooling	32814053
Intra	RNF183	Q96D59	HTRA2	Homo sapiens	O43464	Validated Y2H	32814053
Intra	RNF183	Q96D59	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	RNF183	Q96D59	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	RNF183	Q96D59	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	RNF183	Q96D59	A2M	Homo sapiens	P01023	Y2H Array	32814053
Intra	RNF183	Q96D59	A2M	Homo sapiens	P01023	Validated Y2H	32814053
Intra	RNF183	Q96D59	A2M	Homo sapiens	P01023	Y2H Pooling	32814053
Intra	RNF183	Q96D59	TTR	Homo sapiens	P02766	Validated Y2H	32814053
Intra	RNF183	Q96D59	TTR	Homo sapiens	P02766	Y2H Pooling	32814053
Intra	RNF183	Q96D59	TTR	Homo sapiens	P02766	Y2H Array	32814053
Intra	RNF183	Q96D59	NDUFV2	Homo sapiens	P19404	Validated Y2H	32814053
Intra	RNF183	Q96D59	NDUFV2	Homo sapiens	P19404	Y2H Array	32814053
Intra	RNF183	Q96D59	NDUFV2	Homo sapiens	P19404	Y2H Pooling	32814053
Intra	RNF183	Q96D59	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	RNF183	Q96D59	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	RNF183	Q96D59	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	RNF183	Q96D59	TAX1BP3	Homo sapiens	O14907	Validated Y2H	25416956
Intra	RNF183	Q96D59	TAX1BP3	Homo sapiens	O14907	Y2H Prey Pooling	25416956
Intra	RNF183	Q96D59	LITAF	Homo sapiens	Q99732	Validated Y2H	32814053
Intra	RNF183	Q96D59	LITAF	Homo sapiens	Q99732	Y2H Array	32814053
Intra	RNF183	Q96D59	LITAF	Homo sapiens	Q99732	Y2H Pooling	32814053
Intra	RNF183	Q96D59	FATE1	Homo sapiens	Q969F0	Y2H Prey Pooling	32296183
Intra	RNF183	Q96D59	FATE1	Homo sapiens	Q969F0	Y2H Array	32296183
Intra	RNF183	Q96D59	PRPS1	Homo sapiens	P60891	Validated Y2H	32814053
Intra	RNF183	Q96D59	PRPS1	Homo sapiens	P60891	Y2H Array	32814053
Intra	RNF183	Q96D59	PRPS1	Homo sapiens	P60891	Y2H Pooling	32814053
Intra	RNF183	Q96D59	PRPH	Homo sapiens	P41219	Validated Y2H	32814053
Intra	RNF183	Q96D59	PRPH	Homo sapiens	P41219	Y2H Array	32814053
Intra	RNF183	Q96D59	PRPH	Homo sapiens	P41219	Y2H Pooling	32814053
Intra	RNF183	Q96D59	DBH	Homo sapiens	P09172	Validated Y2H	32814053
Intra	RNF183	Q96D59	DBH	Homo sapiens	P09172	Y2H Pooling	32814053
Intra	RNF183	Q96D59	DBH	Homo sapiens	P09172	Y2H Array	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Hemolytic Disease Of Fetus And Newborn, Rh-Induced

Rh Deficiency Syndrome	Rh Disease
HDFNRH	Rh Fetomaternal Incompatibility
Rh-Null Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12068	RNF183 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	RNF183	VGNC	VGNC:76855
Felis catus	RNF183	VGNC	VGNC:64685
Rattus norvegicus	RNF183	RGD	RGD:1564412
Bos taurus	RNF183	VGNC	VGNC:34041
Mus musculus	RNF183	MGD	MGI:1923322

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RNF183 - ring finger protein 183 Gene

关于 RNF183

功能概要

RNF183 基因产物(7)

RNF183 蛋白结构

RNF183 蛋白互作信息

关联疾病

直系同源

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RNF183 - ring finger protein 183 Gene

关于 RNF183

功能概要

RNF183 基因产物(7)

RNF183 蛋白结构

RNF183 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z