2. Gene
  3. SRARP - steroid receptor associated and regulated protein Gene

SRARP - steroid receptor associated and regulated protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：类固醇受体相关和调节蛋白

种属: Homo sapiens

同用名: ERRF; C1orf64

基因 ID: 149563 | 基因类型: protein coding

关于 SRARP

Cytogenetic location: 1p36.13 Genomic coordinates (GRCh38): 1:16,004,236-16,008,807 (from NCBI)

This gene has 1 transcript (splice variant) and 78 orthologues. Biased expression in endometrium (RPKM 2.9), salivary gland (RPKM 2.4) and 4 other tissues.

功能概要

启用雌激素受体结合活性。参与细胞内雌激素受体信号通路的正向调节。位于细胞质和细胞核中。 [由基因组资源联盟提供，2022 年 4 月]

Enables Estrogen Receptor binding activity. Involved in positive regulation of intracellular Estrogen Receptor signaling pathway. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SRARP 基因产物(1)

mRNA Protein Name
NM_178840.4 NP_849162.1 steroid receptor-associated and regulated protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nuclear estrogen receptor binding IPI
IPI: 通过物理相互作用推断
27125460 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of intracellular estrogen receptor signaling pathway IMP
IMP: 通过突变表型推断
27125460 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
22341523 GOA
located in nucleus IDA
IDA: 通过直接分析推断
22341523 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SRARP 蛋白结构

DUF4654

DUF4654: Domain of unknown function (DUF4654) (32 - 169)

  • 0
  • 100
  • 169 a.a.
蛋白主名 其他名称

steroid receptor-associated and regulated protein

ER-related factor

SRARP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SRARP Q8NEQ6 SLC4A2 Homo sapiens P04920
Anti Tag CoIP
33961781
种属内
SRARP Q8NEQ6 WFS1 Homo sapiens O76024
Validated Y2H
32814053
种属内
SRARP Q8NEQ6 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
种属内
SRARP Q8NEQ6 WFS1 Homo sapiens O76024
Y2H Array
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Lymphocele

Lymph Cyst

Lymphocele Adverse Event
Peyronie'S Disease

Induratio Penis Plastica

Peyronie Disease

Peyronies Disease

Peyronie'S Fibromatosis

Penile Induration

Balanitis Xerotica Obliterans
Urethral Stricture

Ankylurethria

Urethral Stenosis

Urethral Contracture

Urethral Obstruction

Meatal Stenosis Nos

Constriction Of Urethra

Contraction Of Urethra

Stricture Of Urinary Meatus

Urethral Obliteration

Urethral Narrowing

Pinpoint Meatus

Pinhole Meatus Nos

Urethral Occlusion
Laryngomalacia

Congenital Laryngomalacia

Congenital Laryngeal Stridor

Laryngomalacia Congenital

Floppy Epiglottis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13747 SRARP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SRARP VGNC VGNC:107639
Rattus norvegicus SRARP RGD RGD:1566083
Canis familiaris SRARP VGNC VGNC:46789
Mus musculus SRARP MGD MGI:2685540
Macaca mulatta SRARP VGNC VGNC:78008
Bos taurus SRARP VGNC VGNC:35267
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