2. Gene
  3. ZDHHC15 - zinc finger DHHC-type palmitoyltransferase 15 Gene

ZDHHC15 - zinc finger DHHC-type palmitoyltransferase 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指 DHHC 型棕榈酰转移酶 15

种属: Homo sapiens

同用名: MRX91; DHHC15

基因 ID: 158866 | 基因类型: protein coding

关于 ZDHHC15

Cytogenetic location: Xq13.3 Genomic coordinates (GRCh38): X:75,368,427-75,523,037 (from NCBI)

This gene has 3 transcripts (splice variants), 210 orthologues, 17 paralogues and is associated with 1 phenotype. Broad expression in brain (RPKM 1.4), thyroid (RPKM 0.9) and 21 other tissues.

功能概要

该基因编码的蛋白质属于 DHHC 棕榈酰转移酶家族。该基因的突变与智力迟钝 X 连锁 91 型 (MRX91) 相关。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2009 年 9 月]

The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

ZDHHC15 基因产物(3)

mRNA Protein Name
NM_001146256.2 NP_001139728.1 palmitoyltransferase ZDHHC15 isoform 2
NM_001146257.2 NP_001139729.1 palmitoyltransferase ZDHHC15 isoform 3
NM_144969.3 NP_659406.1 palmitoyltransferase ZDHHC15 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables palmitoyltransferase activity IDA
IDA: 通过直接分析推断
23034182 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein-cysteine S-palmitoyltransferase activity IDA
IDA: 通过直接分析推断
18817523 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in peptidyl-L-cysteine S-palmitoylation IDA
IDA: 通过直接分析推断
18817523 GOA
involved in protein localization to membrane IMP
IMP: 通过突变表型推断
18817523 GOA
involved in protein palmitoylation IDA
IDA: 通过直接分析推断
23034182 GOA
involved in protein targeting to Golgi apparatus IMP
IMP: 通过突变表型推断
18817523 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
16647879 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZDHHC15 蛋白结构

DHHC

DHHC: DHHC palmitoyltransferase (70 - 247)

  • 0
  • 100
  • 200
  • 300
  • 337 a.a.
蛋白主名 其他名称

palmitoyltransferase ZDHHC15

DHHC-15

ZDHHC15 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ZDHHC15 Q96MV8 LSMEM1 Homo sapiens Q8N8F7
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 LSMEM1 Homo sapiens Q8N8F7
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 ORMDL1 Homo sapiens Q9P0S3
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 TMEFF2 Homo sapiens Q9UIK5
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 TMEFF2 Homo sapiens Q9UIK5
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 TMEFF2 Homo sapiens Q9UIK5
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 CLRN1 Homo sapiens P58418
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 CLRN1 Homo sapiens P58418
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 TBXA2R Homo sapiens Q0VAB0
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 TBXA2R Homo sapiens Q0VAB0
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 TMEM14C Homo sapiens Q9P0S9
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 MCEMP1 Homo sapiens Q8IX19
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 MCEMP1 Homo sapiens Q8IX19
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 CLEC10A Homo sapiens Q8IUN9
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 CLEC10A Homo sapiens Q8IUN9
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 TMEM222 Homo sapiens Q9H0R3
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 PLLP Homo sapiens Q9Y342
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 PVR Homo sapiens P15151
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 MTIF3 Homo sapiens Q9H2K0
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 TNFRSF10B Homo sapiens O14763
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 TNFRSF10B Homo sapiens O14763
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 TMEM120A Homo sapiens Q9BXJ8
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 YIPF4 Homo sapiens Q9BSR8
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra ZDHHC15 Q96MV8 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra ZDHHC15 Q96MV8 PEX16 Homo sapiens Q9Y5Y5
Validated Y2H
32296183
Intra ZDHHC15 Q96MV8 UBE2J1 Homo sapiens Q9Y385
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spastic Diplegia

Diplegic Infantile Cerebral Palsy

Little'S Disease

Cerebral Palsy

Cerebral Spastic Infantile Paralysis

Infantile Diplegic Cerebral Palsy

Infantile Spastic Cerebral Palsy

Littles Disease

Spastic Cerebral Palsy
Non-Syndromic X-Linked Intellectual Disability 91

Mrx91
Non-Syndromic X-Linked Intellectual Disability 98

Mrx98

X-Linked Mental Retardation 98
Non-Syndromic X-Linked Intellectual Disability 58

Mrx58
Cerebral Palsy, Ataxic, Autosomal Recessive

Ataxic Cerebral Palsy

Acp

Hypotonic Cerebral Palsy

Cerebral Palsy Ataxic

Cerebral Palsy, Atonic

Congenital Cerebral Palsy With Ataxia

Ataxic Cerebral Paralysis

Ataxia With Cerebral Palsy

Cerebral Infantile Diataxia
Tonne-Kalscheuer Syndrome

TOKAS

Mrx61

Intellectual Developmental Disorder With Or Without Hand And Foot Anomalies, Genital Anomalies, Or Congenital Diaphragmatic Hernia

Mental Retardation, X-Linked 61

X-Linked Mental Retardation 61
Inflammatory Bowel Disease 22

IBD22
Cataract 40

CTRCT40

Cataract 40 With Or Without Microcornea

Cct

Cataract, Congenital, X-Linked

Cataract 40, X-Linked

Cataract, Congenital, With Microcornea Or Slight Microphthalmia

Cxn

Cataract, Congenital Total, With Posterior Sutural Opacities In Heterozygotes

Cataract 40 X-Linked

Cataract Congenital X-Linked

Cataract, Total Congenital

Cataract, Total Congenital With Posterior Sutural Opacities In Heterozygotes

Congenital Total Cataract With Posterior Sutural Opacities In Heterozygotes

X-Linked Congenital Cataract

Cataract, Type 40
Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability

Non-Specific X-Linked Mental Retardation

X-Linked Non-Specific Intellectual Disability
Neuronal Ceroid Lipofuscinosis

Hereditary Ceroid Lipofuscinosis

Batten Disease

Ncl

Neuronal Ceroid-Lipofuscinoses

Lipofuscinosis, Ceroid, Neuronal

Juvenile Neuronal Ceroid Lipofuscinosis

Cerebromacular Dystrophy

Cerebromacular Degeneration

Ceroid-Lipofuscinosis

Ncl - [Neuronal Ceroid Lipofuscinosis]

Amaurotic Familial Idiocy

Amaurotic Idiocy

Amaurotic Idiot

Neuronal Lipofuscinosis

Pigmentary Retinal Lipoid Neuronal Heredodegeneration
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16015 ZDHHC15 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ZDHHC15 VGNC VGNC:37130
Canis familiaris ZDHHC15 VGNC VGNC:48581
Mus musculus ZDHHC15 MGD MGI:1915336
Macaca mulatta ZDHHC15 VGNC VGNC:79245
Rattus norvegicus ZDHHC15 RGD RGD:1562075
Felis catus ZDHHC15 VGNC VGNC:67204
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