1. Gene
  2. PLLP - plasmolipin Gene

PLLP - plasmolipin Gene

中文名称:浆磷脂

种属: Homo sapiens

同用名: PMLP; TM4SF11

基因 ID: 51090 | 基因类型: protein coding

关于 PLLP

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:57,256,097-57,284,672 (from NCBI)

This gene has 5 transcripts (splice variants), 201 orthologues and 14 paralogues. Broad expression in brain (RPKM 41.3), stomach (RPKM 28.7) and 17 other tissues.

功能概要

预计是髓鞘的结构成分。预测参与髓鞘形成。预测位于致密髓鞘和膜筏中。预计是膜的组成部分。精神分裂症的生物标志物。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be located in compact myelin and membrane raft. Predicted to be integral component of membrane. Biomarker of schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]

PLLP 基因产物(1)

mRNA Protein Name
NM_015993.3 NP_057077.1 plasmolipin
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
26002055 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in myelin sheath IDA
IDA: 通过直接分析推断
26002055 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
26002055 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PLLP 蛋白结构

MARVEL

MARVEL: Membrane-associating domain (32 - 160)

  • 0
  • 100
  • 182 a.a.
蛋白主名 其他名称

plasmolipin

plasma membrane proteolipid (plasmolipin)

PLLP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PLLP Q9Y342 MS4A12 Homo sapiens Q9NXJ0 32296183
种属内
PLLP Q9Y342 MS4A12 Homo sapiens Q9NXJ0 25416956
种属内
PLLP Q9Y342 MS4A12 Homo sapiens Q9NXJ0 25416956
种属内
PLLP Q9Y342 MS4A12 Homo sapiens Q9NXJ0 32296183
种属内
PLLP Q9Y342 TRIM59 Homo sapiens Q8IWR1 32296183
种属内
PLLP Q9Y342 TRIM59 Homo sapiens Q8IWR1 32296183
种属内
PLLP Q9Y342 TMEM174 Homo sapiens Q8WUU8 32296183
种属内
PLLP Q9Y342 TMEM174 Homo sapiens Q8WUU8 32296183
种属内
PLLP Q9Y342 PGRMC2 Homo sapiens O15173 32296183
种属内
PLLP Q9Y342 PGRMC2 Homo sapiens O15173 32296183
种属内
PLLP Q9Y342 VMA21 Homo sapiens Q3ZAQ7 32296183
种属内
PLLP Q9Y342 VMA21 Homo sapiens Q3ZAQ7 32296183
种属内
PLLP Q9Y342 GPX8 Homo sapiens Q8TED1 32296183
种属内
PLLP Q9Y342 GPX8 Homo sapiens Q8TED1 32296183
种属内
PLLP Q9Y342 TMPPE Homo sapiens Q6ZT21 32296183
种属内
PLLP Q9Y342 TMPPE Homo sapiens Q6ZT21 32296183
种属内
PLLP Q9Y342 CLDN14 Homo sapiens O95500 32296183
种属内
PLLP Q9Y342 CLDN14 Homo sapiens O95500 32296183
种属内
PLLP Q9Y342 CLEC2D Homo sapiens Q9UHP7-3 32296183
种属内
PLLP Q9Y342 CLEC2D Homo sapiens Q9UHP7-3 32296183
种属内
PLLP Q9Y342 MFF Homo sapiens Q9GZY8-5 32296183
种属内
PLLP Q9Y342 MFF Homo sapiens Q9GZY8-5 32296183
种属内
PLLP Q9Y342 KCNJ6 Homo sapiens P48051 32296183
种属内
PLLP Q9Y342 KCNJ6 Homo sapiens P48051 32296183
种属内
PLLP Q9Y342 FNDC9 Homo sapiens Q8TBE3 32296183
种属内
PLLP Q9Y342 FNDC9 Homo sapiens Q8TBE3 32296183
种属内
PLLP Q9Y342 TMPRSS2 Homo sapiens O15393-2 32296183
种属内
PLLP Q9Y342 TMPRSS2 Homo sapiens O15393-2 32296183
种属内
PLLP Q9Y342 CLEC12B Homo sapiens Q2HXU8-2 32296183
种属内
PLLP Q9Y342 CLEC12B Homo sapiens Q2HXU8-2 32296183
种属内
PLLP Q9Y342 ZDHHC15 Homo sapiens Q96MV8 32296183
种属内
PLLP Q9Y342 ZDHHC15 Homo sapiens Q96MV8 32296183
种属内
PLLP Q9Y342 AQP6 Homo sapiens Q13520 32296183
种属内
PLLP Q9Y342 AQP6 Homo sapiens Q13520 32296183
种属内
PLLP Q9Y342 CD164L2 Homo sapiens Q6UWJ8-2 32296183
种属内
PLLP Q9Y342 CD164L2 Homo sapiens Q6UWJ8-2 32296183
种属内
PLLP Q9Y342 GOLT1A Homo sapiens Q6ZVE7 32296183
种属内
PLLP Q9Y342 GOLT1A Homo sapiens Q6ZVE7 32296183
种属内
PLLP Q9Y342 CRB3 Homo sapiens Q9BUF7-2 32296183
种属内
PLLP Q9Y342 CRB3 Homo sapiens Q9BUF7-2 32296183
种属内
PLLP Q9Y342 TMEM167B Homo sapiens Q9NRX6 32296183
种属内
PLLP Q9Y342 TMEM167B Homo sapiens Q9NRX6 32296183
种属内
PLLP Q9Y342 SLC10A6 Homo sapiens Q3KNW5 32296183
种属内
PLLP Q9Y342 SLC10A6 Homo sapiens Q3KNW5 32296183
种属内
PLLP Q9Y342 SYPL2 Homo sapiens Q5VXT5-2 32296183
种属内
PLLP Q9Y342 SYPL2 Homo sapiens Q5VXT5-2 32296183
种属内
PLLP Q9Y342 ELOVL4 Homo sapiens Q9GZR5 32296183
种属内
PLLP Q9Y342 ELOVL4 Homo sapiens Q9GZR5 32296183
种属内
PLLP Q9Y342 FAM174A Homo sapiens Q8TBP5 32296183
种属内
PLLP Q9Y342 FAM174A Homo sapiens Q8TBP5 32296183
种属内
PLLP Q9Y342 RNF122 Homo sapiens Q9H9V4 32296183
种属内
PLLP Q9Y342 RNF122 Homo sapiens Q9H9V4 32296183
种属内
PLLP Q9Y342 STING1 Homo sapiens Q86WV6 32296183
种属内
PLLP Q9Y342 STING1 Homo sapiens Q86WV6 32296183
种属内
PLLP Q9Y342 LHFPL5 Homo sapiens Q8TAF8 32296183
种属内
PLLP Q9Y342 LHFPL5 Homo sapiens Q8TAF8 32296183
种属内
PLLP Q9Y342 CYSRT1 Homo sapiens A8MQ03 32296183
种属内
PLLP Q9Y342 EBP Homo sapiens Q15125 32296183
种属内
PLLP Q9Y342 EBP Homo sapiens Q15125 32296183
种属内
PLLP Q9Y342 SAR1A Homo sapiens Q9NR31 32296183
种属内
PLLP Q9Y342 SAR1A Homo sapiens Q9NR31 32296183
种属内
PLLP Q9Y342 TIGIT Homo sapiens Q495A1 32296183
种属内
PLLP Q9Y342 TIGIT Homo sapiens Q495A1 32296183
种属内
PLLP Q9Y342 PACC1 Homo sapiens Q9H813 32296183
种属内
PLLP Q9Y342 PACC1 Homo sapiens Q9H813 32296183
种属内
PLLP Q9Y342 TNFSF14 Homo sapiens O43557 32296183
种属内
PLLP Q9Y342 TNFSF14 Homo sapiens O43557 32296183
种属内
PLLP Q9Y342 BCL2L13 Homo sapiens Q9BXK5 25416956
种属内
PLLP Q9Y342 BCL2L13 Homo sapiens Q9BXK5 25416956
种属内
PLLP Q9Y342 BCL2L13 Homo sapiens Q9BXK5 25416956
种属内
PLLP Q9Y342 ERGIC3 Homo sapiens Q9Y282 32296183
种属内
PLLP Q9Y342 ERGIC3 Homo sapiens Q9Y282 32296183
种属内
PLLP Q9Y342 TMEM14B Homo sapiens Q9NUH8 32296183
种属内
PLLP Q9Y342 TMEM14B Homo sapiens Q9NUH8 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Usher Syndrome, Type Iiia

Usher Syndrome Type 3

Ush3

Usher Syndrome Type 3a

USH3A

Usher Syndrome, Type Iii

Usher Syndrome, Type 3

Usher Syndrome, Type 3a

Usher Syndrome Type Iiia

Usher Syndrome 3a

Usher'S Syndrome Type 3

Usher Syndrome Iii

Usher Syndrome Type Iii

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Bardet-Biedl Syndrome

Bbs

Biedl-Bardet Syndrome

Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive

Charcot-Marie-Tooth Disease Type 4

Charcot-Marie-Tooth Disease Type 4e

Hereditary Motor And Sensory Neuropathy

Cmt4e

CHN1

Hypomyelinating Neuropathy, Congenital, 1

Charcot-Marie-Tooth Neuropathy Type 4e

Neuropathy, Congenital Hypomyelinating, 1

Ar-Cmt1

Autosomal Recessive Demyelinating Charcot-Marie-Tooth

Cmt4

Neuropathy, Congenital Hypomyelinating Or Amyelinating, Autosomal Recessive

Hypomyelination, Severe Congenital

Charcot-Marie-Tooth Disease, Type 4e

Charcot-Marie-Tooth Neuropathy, Type 4e

Autosomal Recessive Congenital Hypomyelinating Or Amyelinating Neuropathy

Autosomal Recessive Congenital Hypomyelinating Neuropathy

Congenital Amyelinating Neuropathy

Congenital Hypomyelinating Neuropathy Autosomal Recessive

Neuropathy, Congenital Hypomyelinating Or Amyelinating

Severe Congenital Hypomyelination

Hereditary Sensory Motor Neuropathy

Charcot-Marie-Tooth Disease, Demyelinating, Autosomal Recessive

Neuropathy, Hypomyelinating, Congenital, Type 1

Neuropathy, Motor And Sensory, Hereditary

Congenital Hypomyelinating Neuropathy

Hereditary Motor And Sensory Neuropathies

Hereditary Sensorimotor Neuropathy

Hmsn - [Hereditary Motor And Sensory Neuropathy]

Hsmn - [Hereditary Sensory And Motor Neuropathy]

Hereditary Motor And Sensory Neuropathy, Types I-Iv

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus PLLP VGNC VGNC:33037
Canis familiaris PLLP VGNC VGNC:44699
Rattus norvegicus PLLP RGD RGD:621478
Mus musculus PLLP MGD MGI:1915051
Macaca mulatta PLLP VGNC VGNC:99579