2. Gene
  3. Cxcl10 - chemokine (C-X-C motif) ligand 10 Gene

Cxcl10 - chemokine (C-X-C motif) ligand 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10

基因 ID: 15945 | 基因类型: protein coding

关于 Cxcl10

功能概要

Predicted to enable chemoattractant activity; Chemokine Receptor binding activity; and heparin binding activity. Acts upstream of or within several processes, including defense response to virus; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including alimentary system; axial skeleton; hemolymphoid system; and liver. Human ortholog(s) of this gene implicated in hepatitis B; middle cerebral artery infarction; and type 1 diabetes mellitus. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10). [provided by Alliance of Genome Resources, Apr 2022]

Cxcl10 基因产物(1)

mRNA Protein Name
NM_021274.2 NP_067249.1 C-X-C motif chemokine 10 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-17 IDA
IDA: 通过直接分析推断
30294880 MGI
acts upstream of or within defense response to virus IDA
IDA: 通过直接分析推断
17277142 MGI
acts upstream of or within negative regulation of myoblast differentiation IMP
IMP: 通过突变表型推断
23844157 MGI
acts upstream of or within negative regulation of myoblast fusion IMP
IMP: 通过突变表型推断
23844157 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
19008373 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
11894098 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-X-C motif chemokine 10

10 kDa interferon gamma-induced protein

gamma-IP10

interferon activated gene 10

interferon-gamma induced protein CRG-2

small inducible cytokine B subfamily (Cys-X-Cys), member 10

small-inducible cytokine B10

重组 Cxcl10 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7227 IP-10/CRG-2/CXCL10 Protein, Mouse P17515 (I22-P98) ≥95%
HY-P700168AF Animal-Free IP-10/CRG-2/CXCL10 Protein, Mouse (His) P17515 (I22-P98) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99190 Eldelumab Inhibitor 96.76% Phase 2
Pre-clinical Phase
生物活性分子 (18)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15319 AMG 487 Inhibitor 99.65% 否
HY-15589 GW9508 99.33% 否
HY-15320 NBI-74330 Antagonist 98.57% 否
HY-111149A PS372424 hydrochloride Agonist ≥98.0% 否
HY-152237 TBK1-IN-1 Inhibitor 99.91% 否
HY-152956 STING agonist-23 Agonist 99.16% 否
HY-124151 Adenosine-2'-monophosphate Activator 99.91% 否
HY-152959 STING agonist-26 Agonist 99.56% 否
HY-111149 PS372424 Agonist / 否
HY-122891 SB02024 / 否
HY-RS03384 CXCL10 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-152957 STING agonist-24 Agonist / 否
HY-152958 STING agonist-25 Agonist / 否
HY-152961 STING agonist-28 Agonist / 否
HY-15319A (±)-AMG 487 Inhibitor / 否
HY-162675 COB-187 Inhibitor / 否
HY-W104821 Rosolic acid Activator / 否
HY-113730 VUF5834 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cxcl10 NCBI NCBI:3627
Susscrofa domestica Cxcl10 NCBI
Rattus norvegicus Cxcl10 NCBI NCBI:245920
Macaca mulatta Cxcl10 NCBI NCBI:574243
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