2. Gene
  3. Cxcl10 - C-X-C motif chemokine ligand 10 Gene

Cxcl10 - C-X-C motif chemokine ligand 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: IP-10; Scyb10

基因 ID: 245920 | 基因类型: protein coding

关于 Cxcl10

功能概要

Enables chemokine activity. Involved in several processes, including response to auditory stimulus; response to gamma radiation; and response to vitamin D. Located in extracellular space. Used to study adult respiratory distress syndrome; myocarditis; proteinuria; renovascular hypertension; and type 1 diabetes mellitus. Biomarker of brain ischemia; encephalitis; and uveitis. Human ortholog(s) of this gene implicated in hepatitis B and middle cerebral artery infarction. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10). [provided by Alliance of Genome Resources, Apr 2022]

Cxcl10 基因产物(1)

mRNA Protein Name
NM_139089.2 NP_620789.2 C-X-C motif chemokine 10 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemokine activity IDA
IDA: 通过直接分析推断
9288136 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to heat IEP
IEP: 通过表达模式推断
17457469 RGD
involved in immune response IDA
IDA: 通过直接分析推断
12023393 RGD
involved in negative regulation of angiogenesis IDA
IDA: 通过直接分析推断
9288136 RGD
involved in positive regulation of cell migration IDA
IDA: 通过直接分析推断
8798675 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
8798675 RGD
involved in positive regulation of leukocyte chemotaxis IDA
IDA: 通过直接分析推断
9288136 RGD
involved in response to auditory stimulus IEP
IEP: 通过表达模式推断
15519684 RGD
involved in response to gamma radiation IEP
IEP: 通过表达模式推断
19084914 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
9288136 RGD
involved in response to vitamin D IEP
IEP: 通过表达模式推断
15637289 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17457469 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-X-C motif chemokine 10

10 kDa interferon gamma-induced protein

chemokine (C-X-C motif) ligand 10

gamma-IP10

interferon-inducible cytokine IP-10

interferon-inducible protein 10

protein Mob-1

small inducible cytokine B subfamily (Cys-X-Cys) member 10

small inducible cytoki

重组 Cxcl10 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7225 IP-10/CXCL10 Protein, Rat (HEK293) P48973 (I22-P98) ≥95%
HY-P74797 IP-10/CXCL10 Protein, Rat (P.pastoris, His) P48973/NP_620789 (I22-P98) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99190 Eldelumab Inhibitor 96.76% Phase 2
Pre-clinical Phase
生物活性分子 (19)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15319 AMG 487 Inhibitor 99.65% 否
HY-15589 GW9508 99.33% 否
HY-152237 TBK1-IN-1 Inhibitor 99.91% 否
HY-15320 NBI-74330 Antagonist 98.57% 否
HY-111149A PS372424 hydrochloride Agonist ≥98.0% 否
HY-152956 STING agonist-23 Agonist 99.16% 否
HY-124151 Adenosine-2'-monophosphate Activator 99.91% 否
HY-122891 SB02024 99.7% 否
HY-152959 STING agonist-26 Agonist 99.56% 否
HY-111149 PS372424 Agonist / 否
HY-RS03384 CXCL10 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-152957 STING agonist-24 Agonist / 否
HY-152958 STING agonist-25 Agonist / 否
HY-152961 STING agonist-28 Agonist / 否
HY-15319A (±)-AMG 487 Inhibitor / 否
HY-162675 COB-187 Inhibitor / 否
HY-W104821 Rosolic acid Activator / 否
HY-113730 VUF5834 / 否
HY-167884 PF-1367550 Inhibitor / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990639 NI-0801 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cxcl10 NCBI NCBI:3627
Mus musculus Cxcl10 NCBI NCBI:15945
Susscrofa domestica Cxcl10 NCBI
Macaca mulatta Cxcl10 NCBI NCBI:574243
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